This paper seeks to evaluate crack propagation properties and residual lives of metallic alloys subjected to fatigue loading at room and high temperatures. Fatigue crack growth tests were performed on Ti-6Al-4V/ELI and 7050-T7452 subjected to constant-amplitude and actual random-spectra loading at room temperature of about 25 degrees C and at high temperatures of 250 degrees C and 150 degrees C to determine their crack growth properties and residual lives. The damage mode and mechanisms at high temperature were compared with those at room temperature on the basis of the results of fractographic analysis. Temperature-dependent residual lives under actual random-spectra load history were evaluated based on a modified accumulation damage rule accounting for the load interaction. Good correlation was achieved between the predictions and actual experiments, demonstrating the practical and effective use of the proposed method. (C) 2017 Chinese Society of Aeronautics and Astronautics. Production and hosting by Elsevier Ltd.