A methodology on time-domain fluorescence diffuse optical tomography based on GPU-accelerated Monte-Carlo modeling

被引:0
作者
Yi, Xi [1 ]
Wu, Linhui [1 ]
Wang, Xin [1 ]
Chen, Weiting [1 ]
Zhang, Limin [1 ]
Zhao, Huijuan [1 ]
Gao, Feng [1 ]
机构
[1] School of Precision Instrument and Optoelectronics Engineering, Tianjin University
来源
Zhongguo Jiguang/Chinese Journal of Lasers | 2013年 / 40卷 / 05期
关键词
Fluorescence diffuse optical tomography; Generalized pulse spectrum technique; Graphics processing unit; Medical optics; Monte-Carlo simulation; Time-domain;
D O I
10.3788/CJL201340.0504002
中图分类号
学科分类号
摘要
A graphics processing unit (GPU) accelerated Monte Carlo (MC) approach is developed for modeling photon migration in an arbitrarily complex turbid medium, where the diffusion equation (DE) might behave an ineffective modeling tool. Then an image reconstruction algorithm of time-domain fluorescence diffuse optical tomography is proposed based on the developed GPU-accelerated MC calculations, within the framework of the generalized pulse spectrum technique. Simulated results show that the MC-based approach retrieves on the position and shape of the targets in complexly structured domain that include low absorbing and high scattering, low absorbing and low scattering, high absorbing and low scattering, high absorbing and high scattering, and/or void regions, with higher accuracy than the DE-based one, demonstrating the improved generality of the proposed method.
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