Infection of human T-lymphotropic virus type I in patients with cutaneous T-cell lymphoma

被引：0

作者：

Gao, Hong-Yang ^{[1
]}

Shan, Yi-Fei ^{[1
]}

Wang, Ping ^{[2
]}

Qiu, Bing-Sen ^{[2
]}

Wang, Song-Mei ^{[1
]}

机构：

[1] Laboratory of Molecular Biology, School of Medicine, Fudan University, Shanghai 200032, China

[2] Shanghai Institute of Dermatology, Shanghai 200040, China

来源：

Fudan University Journal of Medical Sciences | 2002年 / 29卷 / 01期

关键词：

Blood; -; Cells; DNA; Tissue; Tumors; Viruses;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Purpose: Study the infection of human T-lymphotropic virus type I(HTLV-I) in patients with cutaneous T-cell lymphoma(CTCL). Methods: Detecting antibodies to HTLV-I in serum of patients with CTCL and testing pre-virus DNA of HTLV-I in CTCL patients' periphery blood and tumor tissues. Results: 57 cases of CTCL patients' periphery blood were tested by PCR and pre-virus DNA were found in 6 cases. 54 cases were detected by ELISA and 1 case was thought to be questionable positive. 18 cases were examined by western blot and 4 cases were found to have HTLV-I antibodies and PCR results of these 4 cases are also positive. Conclusions: HTLV-I infection is found in patients with CTCL. There is some relationship between HTLV-I and CTCL.

引用

页码：36 / 38