共 50 条
- [45] Modeling, Synthesis, and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahyro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(4-isobutoxy-3-isopropylphenyl)amino)nicotinic Acid (NEt-4IB) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (22)
- [47] CONVERSION OF OA-6129-B2 INTO (5R,6R)-6-[(R)-1-FLUOROETHYL]-7-OXO-3-[N,N,N'-TRIMETHYLCARBAMIMIDOYL)METHYL]THIO-1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID (88617) JOURNAL OF ANTIBIOTICS, 1989, 42 (10): : 1520 - 1522
- [48] Metabolism and excretion of (S)-6-(3-cyclopentyl-2-(4-trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid (PF-04991532), a hepatoselective glucokinase activator, in humans: confirmation of the MIST potential noted in first-in-Human metabolite scouting studies XENOBIOTICA, 2019, 49 (12) : 1447 - 1457
- [49] Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN) JOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (19) : 8924 - 8940
- [50] Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (LFA-1): Structure-Activity Relationships Leading to the Identification of 6-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic Acid (BMS-688521) JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (09) : 3814 - 3830