Performance of Lattice Structure Scaffold Prepared via Digital Light Processing Manufacture by DLP Technology

被引：0
作者：
Hua S. [1 ,2 ]
Zhu H. [3 ]
Wu J. [1 ,2 ]
Zhai Z. [1 ,2 ]
Chen S. [1 ,2 ]
Liu K. [4 ]
Cheng L. [1 ,2 ]
Xiao J. [3 ]
Shi Y. [1 ,2 ]
机构：
[1] State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan
[2] Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan
[3] Department of Orthopedic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan
[4] School of Materials Science and Engineering, Wuhan University of Technology, Wuhan
来源：
Kuei Suan Jen Hsueh Pao/Journal of the Chinese Ceramic Society | 2021年 / 49卷 / 04期
关键词：
Additive manufacturing hydroxyapatite scaffolds; Biological evaluations; Digital light processing; Lattice structure; Photoinhibitor;
D O I：
10.14062/j.issn.0454-5648.20200572
中图分类号：
学科分类号：
摘要：
Bone defects caused by trauma, bone tumor resection, traffic accidents, etc. increase the demand for bone scaffolds and additive manufacturing technology is gradually being widely used in the preparation of bone scaffolds. Three lattice-structured hydroxyapatite (Ca10(PO4)6OH2), HA ceramic green body such as Diamond structure, Rhombic dodecahedron structure and Octet truss structure were manufactured by Digital Light Processing technology and then successfully sintered three kinds of lattice structure HA ceramic scaffolds with a porosity of 70%, and the minimum pore size after sintering is about 200-300 μm. After being sintered at 1 300℃, the HA ceramic is partially decomposed into β-Ca3(PO4)2, and the ceramic grains are tightly bound. Mechanical strength simulation matches actual results, the average compressive strength of the Octet truss structure is the largest, which is 3.16 MPa. In vitro cell experiments showed that the surface of the HA ceramic bone scaffold is beneficial to the spread and adhesion of bone mesenchymal stem cells (rBMSCs), and the HA ceramic prepared by DLP has good biocompatibility. Therefore high-precision lattice structure HA ceramic bone scaffold fabricated by DLP technology is expected to be widely used in bone tissue engineering. © 2021, Editorial Department of Journal of the Chinese Ceramic Society. All right reserved.
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页码：608 / 617
页数：9
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