SiGe/Si heterostructure is characterized using HREM, synchrotron radiation X-ray topography, and secondary ion mass spectrometry (SIMS). Many defects distribute in the SiGe layer, but few and even no defects are found else layers. The mechanism of defects is discussed. The doped boron (B) atoms in SiGe layer are favored of replacing germanium atoms in (111) plane. The misfit stress between SiGe layer and Si buffer layer are relaxed by boron doping and lattice deformation related to the doping.