In this study, a comparative evaluation of bio-augmentation prospects for the management of Segre-gated Putrescible Municipal Solid Waste (SPMSW) has been carried out. Six parameters under three heads that are Degradability (TOC%, C: N ratio) Nutrient release efficacy (TKN%, E.C. & TK%), and Change in Medium (pH) were examined and results were further analyzed. In comparison to Seeded Microbial Composting (SMC); the Secondary Decomposer Bio-augmentation (SDB) resulted in a greater rate of TOC% degradation, C: N ratio reduction, rise in availability of TKN%, E.C., and TK%. The value observed at the final day of treatment had remarkable difference (0.05% level of signifi-cance). Due course of degradation it was observed that pH was reeling towards neutral range in SDB while to the acidic in SMC. In SDB, priming could be the reason of faster, better, and time-efficient manuring than SMC, which is availed by Secondary decomposers that were boosting the decomposi-tion process. In SDB priming could be the reason which has been availed by secondary decomposers that were boosting the decomposition process which exhibited in the form of faster, better, and time-efficient manuring than SMC. © 2022 Widener University School of Civil Engineering. All rights reserved.