In the framework of kinetic theory of rough spheres (KTRS) model, a dynamic coefficient of restitutionmodel is introduced to describe the collision behavior between wet rough particles in liquid. Based onthe two-fluid model (TFM) combining kinetic theory of rough spheres, numerical simulations are con-ducted on the flow characteristic of rough particles and liquid in a pulsed fluidized bed. The simulationresults are firstly validated against experimental data reported by Ehsani et al. Subsequently, the effectsof pulsation flow on liquid-solid two-phase flow, particle collision and particle rotation behavior arestudied. The results indicate that resonance fluidization occurs at a frequency of 1 Hz, which isapproached to the natural frequency of the bed. Furthermore, the particle volume fraction increases withthe pulsation amplitude at this frequency. Conversely, at a frequency of 36 Hz, the volume fraction exhi-bits the opposite trend with the pulsation amplitude. The interstitial fluid increases the dissipation ofkinetic energy in particle collision, though its effect is much smaller than that caused by particle rotation.& Oacute;2024 The Society of Powder Technology Japan. Published by Elsevier BV and The Society of PowderTechnology Japan. All rights are reserved, including those for text and data mining, AI training, andsimilar technologies.