Research Progress on Structural Characterization of Polysaccharides from Natural Resources

被引：0
作者：
Xie M. [1 ]
Yin J. [1 ]
Nie S. [1 ]
机构：
[1] State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang
来源：
Journal of Chinese Institute of Food Science and Technology | 2017年 / 17卷 / 03期
关键词：
Methylation; NMR; Partial degradation; Polysaccharide; Research progress; Structure;
D O I：
10.16429/j.1009-7848.2017.03.001
中图分类号：
学科分类号：
摘要：
Polysaccharides existing in advanced plant, animal and microorganism are one of very important natural macromolecules. Many bioactive polysaccharides have good effects on immune modulation, anti-tumor, anti-oxidant and gut bacteria regulation bioactivities. The clearly elucidating in polysaccharide structure would guide deeply understanding their bioactivities and be beneficial for the basic structure research and applications. In this paper, it is briefly introduced about the isolation, purification and structural elucidation strategies of polysaccharides from natural resources. Research progress is highly emphasized on structural characterization of glucan, glucomannan, xyloglucan, arabinoxylan and pectin. We also propose some problems in the present research and point out our own view. We suggest that the combined utilization of partial degradation, methylation and NMR could be taken as the key method for polysaccharide structural elucidation, by reviewing lots of research papers and summarizing our own experiences. Meanwhile, other methods such as ESI-MS, Maldi-Tof-MS and ion mobility-mass spectrometry could also be used additionally to establish a advanced and systematic method for fine structure characterization of polysaccharides. © 2017, Editorial Office of Journal of CIFST. All right reserved.
引用
收藏
页码：1 / 19
页数：18
相关论文
共 135 条
  • [1] Lowe J.B., Marth J.D., A genetic approach to mammalian glycan function, Annual Review of Biochemistry, 72, 1, pp. 643-691, (2003)
  • [2] Liu L., Nie S., Xie M., Et al., Tumor microenvironment as a new target for tumor immunotherapy of polysaccharides, Critical Reviews in Food Science and Nutrition, 56, pp. S85-S94, (2016)
  • [3] Kang S.W., Min H.Y., Ginseng, the 'immunity boost': the effects of Panax ginseng on immune system, Journal of Ginseng Research, 36, 4, pp. 354-368, (2012)
  • [4] Ramberg J.E., Nelson E.D., Sinnott R.A., Immunomodulatory dietary polysaccharides: a systematic review of the literature, Nutrition Journal, 9, 1, (2010)
  • [5] Cobb B.A., Wang Q., Tzianabos A.O., Et al., Polysaccharide processing and presentation by the MHCII pathway, Cell, 117, 5, pp. 677-687, (2004)
  • [6] Li W.J., Li L., Zhen W.Y., Et al., Ganoderma atrum polysaccharide ameliorates ROS generation and apoptosis in spleen and thymus of immunosuppressed mice, Food and Chemical Toxicology, 99, pp. 199-208, (2017)
  • [7] Meng X., Liang H., Luo L., Antitumor polysaccharides from mushrooms: a review on the structural characteristics, antitumor mechanisms and immunomodulating activities, Carbohydrate Research, 424, pp. 30-41, (2016)
  • [8] Zhang W., Xu P., Zhang H., Pectin in cancer therapy: a review, Trends in Food Science & Technology, 44, 2, pp. 258-271, (2015)
  • [9] Zong A., Cao H., Wang F., Anticancer polysaccharides from natural resources: A review of recent research, Carbohydrate Polymers, 90, 4, pp. 1395-1410, (2012)
  • [10] Wu Q., Liu L., Miron A., Et al., The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview, Archives of Toxicology, 90, 8, pp. 1817-1840, (2016)
12345678910