Strong double network hydrogels reinforced by silk fibroin microfibers

被引：0
|
作者：
Ma M.-Y. [1 ]
Liu S.-H. [1 ]
Chen S.-F. [1 ]
机构：
[1] College of Chemical and Biological Engineering, Zhejiang University, Hangzhou
来源：
Gao Xiao Hua Xue Gong Cheng Xue Bao/Journal of Chemical Engineering of Chinese Universities | 2021年 / 35卷 / 01期
关键词：
Double network; Mechanical property; Physical crosslinking; Silk fibroin; Tough hydrogel;
D O I：
10.3969/j.issn.1003-9015.2021.01.017
中图分类号：
学科分类号：
摘要：
Traditional hydrogels are too weak to meet the requirements of strength in tissue engineering. A strategy of strengthening was proposed that combined traditional linear hydrophilic polymers with SF nano-fiber. Silk fibroin (SF) is a biocompatible natureprotein which can be applied as a strengthening material by physically crosslinked with microfiber networks. Two double network hydrogels, hydroxyethyl methacrylate/silk fibroin(HEMA/SF) and methacrylamide/silk fibroin (MAA/SF), were prepared through a one-pot method. The results show that the double network hydrogels improve strength by 5-10 times and also increase modulus and energy absorption after being reinforced by SF microfiber network. Compared with chemically crosslinked double network hydrogels, the physically crosslinked double network hydrogel is tougher and more reversible. © 2021, Editorial Board of "Journal of Chemical Engineering of Chinese Universities". All right reserved.
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页码：148 / 154
页数：6
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