Synthesis, characterization and antibacterial activity of cationic nanopolymer

Cationic nanopolymers were prepared by micellar copolymerization of methylmathacrylate (MMA) with methacryloxyethyldimethylhexadecyl ammonium bromide (MDHB). The particle size, zeta potential and molecular weight of the polymers were measured, and the structures were characterized by FT-IR,1H NMR and TG. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration(MBC) of this kind of polymer against E. Coli and S. aureus were tested using a broth dilution test. The results shown that the concentration of MDHB plays a key role in structural characteristics and antibacterial properties of the products. With increasing of MDHB in recipe, particle size and antibacterial activity increase, zeta potential and molecular weight decrease. The polymers have good thermal stability, so they can be blended with common polymer matrix to prepare antibacterial materials. Therefore this kind of polymer is expected to be a promising antibacterial agent for development and application. © 2015, Chongqing Functional Materials Periodical Press Co. Ltd. All right reserved.