Cyano migration-mediated radical-polar crossover cyclopropanation

被引：0

作者：

Ziqiang Wang ^{[1
,2
]}

Yasu Chen ^{[2
]}

Jie Li ^{[1
]}

Chen Zhu ^{[1
,2
]}

机构：

[1] Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science,Soochow University

[2] Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University

来源：

Science China(Chemistry) | 2025年 / 68卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O621.251 [];

学科分类号：

070303 ; 081704 ;

摘要：

We report a novel cyano migration-mediated radical-polar crossover process, whereby both the sulfonylcyanation of aliphatic alkenes and the formation of cyclopropanes are concurrently achieved. This transformation yields a diverse array of multisubstituted cyclopropanes under mild photocatalytic conditions. Mechanistic studies elucidate that the reaction proceeds via intramolecular nucleophilic substitution, leading to the formation of the cyclopropane derivatives.

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页码：241 / 248

页数：8

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