Studies on the Antihypertensive Activity of Bioactive Peptides in Jinhua Dry-cured Ham

被引：0

作者：

Xing L. ^{[1
]}

Zuo Q. ^{[1
]}

Hao Y. ^{[1
]}

Fu L. ^{[1
]}

Zhang W. ^{[1
]}

机构：

[1] Natjonal Center of Meat Qualjty and Safety Control, College of Food Scjence Technology, Nanjing Agrjcultural Unjversjty, Nanjing

来源：

Journal of Chinese Institute of Food Science and Technology | 2023年 / 23卷 / 01期

关键词：

bioactive peptides; blood pressure; Jinhua ham; renin inhibition; spontaneously hypertensive rats;

D O I：

10.16429/j.1009-7848.2023.01.014

中图分类号：

学科分类号：

摘要：

Dry-cured ham possesses many bioactive peptides produced from muscle degradation during the whole process. In order to investigate the antihypertensive activity of bioactive peptides in dry-cured ham, Jinhua ham was chosen to isolate the peptides with measuring their renin regulating effect jn vjtro as well as the blood pressure regulating capacity jn vjvo. Known from the results, the Jinhua ham peptides had the suppressing effect on renin under the mass concentration of 10 mg/mL with the inhibition rate of 62.21[. In spontaneously hypertensive rats (SHR), ham derived peptides were gavaged with the measurements of diastolic and systolic blood pressure. In the treatment of 20 mg/mL peptides, diastolic and systolic blood pressure was significantly decreased compared with control, which showed the similar effect with 5 mg/mL of captopril clinical. However, the suppressing effect of Jinhua ham peptides lasted longer than captopril. In summary, the peptides in Jinhua dry-cured ham had significant antihypertensive activity supplying the potential to carry out the further research on the physiological regulation function of bioactive peptides in dry-cured hams. © 2023 Chinese Institute of Food Science and Technology. All rights reserved.

引用

页码：135 / 142

页数：7

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