Research Progress on Characteristics of Human Microplastic Pollution and Health Risks

被引：2
|
作者：
Ma M.-D. [1 ]
Zhao Y.-C. [1 ]
Zhu L. [1 ]
Wang W.-P. [2 ]
Kang Y.-L. [1 ]
An L.-H. [1 ]
机构：
[1] State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing
[2] Shandong Provincial WeifangEco-environmentMonitoringCenter, Weifang
来源：
Huanjing Kexue/Environmental Science | 2024年 / 45卷 / 01期
关键词：
exposure routes; health risk; microplastics; molecular mechanism; toxicological effects;
D O I：
10.13227/j.hjkx.202212185
中图分类号：
学科分类号：
摘要：
Microplastic pollution is not only an environmental problem but also a social problem. Many studies have been conducted on the sources，abundance，and distribution of microplastics in the environment，but an understanding of human exposure levels and potential health risks remains very limited. Based on the bibliometric methods，the present review systematically summarized the exposure pathways of microplastics in humans，and then the characteristics and potential adverse impacts on human health were expounded upon. Available literature showed that microplastics in human bodies were mainly concentrated on sizes smaller than 50 μm，and polyethylene（PE），polypropylene（PP），and polyethylene terephthalate（PET）were the main polymers. Microplastics in environments entered human bodies mainly through food and respiratory pathways，then accumulated in lung and gastrointestinal tissues. Most importantly，small-sized microplastics could distribute in tissues and organs via the circulatory system. The results from lab-based toxicological experiments showed that microplastics not only posed threats to cell membrane integrity，immune stress，gut microbiota，and energy metabolism but also had potentially adverse impacts on the reproductive system. To further understand the health risks of microplastic pollution，it is necessary to promote research on the toxicological effects of microplastics as well as the inner mechanisms and also to establish risk assessment frameworks for evaluating microplastic pollution. These works are crucial to preventing the risks of microplastic pollution with scientific evidence. © 2024 Science Press. All rights reserved.
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页码：459 / 469
页数：10
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