Nano temperature-switchable supramolecular solvent: Preparation, characterization and application in efficient extraction and enrichment of phytochemicals

被引：0

作者：

Liu L. ^{[1
]}

Zhao X.-T. ^{[1
]}

Cai Z.-H. ^{[1
]}

Liu Y.-H. ^{[1
]}

Zhou Q. ^{[1
]}

Liu G.-S. ^{[1
]}

Dong X.-Y. ^{[1
]}

Fu Y.-J. ^{[1
,2
,3
]}

机构：

[1] The College of Forestry, Beijing Forestry University, Beijing

[2] State Key Laboratory of Efficient Production of Forest Resources, Beijing Forestry University, Beijing

[3] Ecological Observation and Research Station of Heilongjiang Sanjiang Plain Wetlands, National Forestry and Grassland Administration, Shuangyashan

来源：

Journal of Molecular Liquids | 2024年 / 408卷

基金：

中国国家自然科学基金;

关键词：

Efficient extraction; Nanomaterial; Phytochemicals; Supramolecular solvents; Temperature-switchable;

D O I：

10.1016/j.molliq.2024.125221

中图分类号：

学科分类号：

摘要：

In this study, a nano temperature-switchable supramolecular solvent (NTS-SUPRAS) system was designed, prepared and characterized for efficient extraction and enrichment of phytochemicals, the extraction mechanism was also investigated. The NTS-SUPRAS was synthesized by natural deep eutectic (NADES), 1,2-Propanediol and water, then the ternary phase diagrams were plotted according to their mass fractions. Dynamic light scattering (DLS), conductivity and FT-IR were used to characterize the solvent, and an exciting discovery was the nanoscale of NTS-SUPRAS. The particle size of its reverse micelles self- aggregated was positively correlated to the water content, which was increased from 3.8 nm to 77.9 nm as the water content increased from 5 % to 20 %. Temperature-switchable of NTS-SUPRAS was proved by the appearance of phase separation when regulate temperature from 25 °C to 10 °C. Then, six phytochemicals in Cajanus cajan (Linn.) leaves were efficiently extracted and enriched by vortex-assisted extraction. The extraction factors such as solid–liquid ratio, vortex time, NADES content and water content were optimized using the one-factor optimization method and response surface analysis to obtain the optimal extraction conditions. The results showed that the extraction efficiency of NTS-SUPRAS was 1.18–2.32 folds higher than that of traditional solvents for different polar substances, and the total extraction yield could be reached 21.13 mg/g. The phytochemicals were highly recovered by temperature-switching and macroporous adsorption resin with a recovery rate up to 98.6 %, and the reusability of NTS-SUPRAS could still keep at 90.43 % of the initial one after three cycles. Finally, the extraction mechanism of NTS-SUPRAS was investigated using density functional theory (DFT), founding that the hydrogen bonding between NTS-SUPRAS and the phytochemicals was attributed to the high extraction rate. This nano temperature-switchable supramolecular solvent has the advantages of green, low cost, simple preparation, high extraction rate, easy recycling and good reusability, which is suitable for industrialized application and production. In addition, the nanoscale and the temperature-switchable characteristics also provide new prospects for high-value utilization of phytochemicals. © 2024

引用

共 42 条

[1]

Bagherzadeh R., Gorji M., Sorayani Bafgi M.S., Saveh-Shemshaki N., Electrospun conductive nanofibers for electronics, In Electrospun Nanofibers, pp. 467-519, (2017)

[2]

Baig N., Kammakakam I., Falath W., Nanomaterials: a review of synthesis methods, properties, recent progress, and challenges, Mater. Adv., 2, 6, pp. 1821-1871, (2021)

[3]

Ballesteros-Gomez A., Sicilia M.D., Rubio S., Supramolecular solvents in the extraction of organic compounds. A review, Anal. Chim. Acta, 677, 2, pp. 108-130, (2010)

[4]

Cai Z.-H., Liu L., Gu Q., Wang J.-D., Liu G.-S., Zhou Q., Fu Y.-J., Novel natural deep eutectic solvent-based supramolecular solvents designed for extracting phytochemicals from pigeon pea leaves and its scale-up and recovery process, Ind. Crop. Prod., 204, (2023)

[5]

Cai Z.-H., Wang J.-D., Liu L., Ruan L.-D., Gu Q., Yan X.-Y., Fu Y.-J., A green and designable natural deep eutectic solvent-based supramolecular solvents system: Efficient extraction and enrichment for phytochemicals, Chem. Eng. J., 457, (2023)

[6]

Li J., Wu F., Zhang Y., Feng J., Wang X., Yang Y., Wang Z., Zhang H., Application of supramolecular solvent based on the surface-active ionic liquid in dispersive liquid–liquid microextraction of triazine herbicides in tea samples, Food Chem., 399, (2023)

[7]

Che Sulaiman I.S., Basri M., Fard Masoumi H.R., Chee W.J., Ashari S.E., Ismail M., Effects of temperature, time, and solvent ratio on the extraction of phenolic compounds and the anti-radical activity of Clinacanthus nutans Lindau leaves by response surface methodology, Chem. Cent. J., 11, 1, (2017)

[8]

Chen X., Wang R., Tan Z., Extraction and purification of grape seed polysaccharides using pH-switchable deep eutectic solvents-based three-phase partitioning, Food Chem., 412, (2023)

[9]

Duenas Mas M.J., de Dios-Perez C., Ballesteros-Gomez A., Rubio S., Supramolecular solvent extraction and ambient mass spectrometry for the determination of organic contaminants in food packaging material, Chemosphere, 324, (2023)

[10]

Harish V., Tewari D., Gaur M., Yadav A.B., Swaroop S., Bechelany M., Barhoum A., Review on nanoparticles and nanostructured materials: bioimaging, biosensing, drug delivery, tissue engineering, antimicrobial, and agro-food applications, Nanomaterials (Basel), 12, 3, (2022)

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