Improving biocompatibility and corrosion resistance of anodized AZ31 Mg alloy by electrospun chitosan/mineralized bone allograft (MBA) nanocoatings

被引：12
作者：
Rahimi M. [1 ]
Mehdinavaz Aghdam R. [1 ]
Sohi M.H. [1 ]
Rezayan A.H. [2 ]
Ettelaei M. [1 ]
机构：
[1] School of Metallurgy and Materials Engineering, College of Engineering, University of Tehran, P.O. Box: 11155-4563, Tehran
[2] Division of Nanobiotechnology, Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, P.O. Box: 11155-4563, Tehran
来源：
Surface and Coatings Technology | 2021年 / 405卷
关键词：
AZ31 magnesium alloy; Biocompatibility; Chitosan; mineralized bone allograft (MBA); Corrosion; Electrospinning;
D O I：
10.1016/j.surfcoat.2020.126627
中图分类号：
学科分类号：
摘要：
A novel nanofibrous coating containing chitosan and mineralized bone allograft (MBA) nanoparticles was fabricated on AZ31 magnesium alloy via electrospinning in order to enhance corrosion and biocompatibility behavior in a physiological environment. A number of specimens were initially anodized to assess its effect on the improvement of the adhesion between the electrospun nanofibrous coating and the substrate. The coated materials were characterized by using SEM, EDS, FT-IR, and TG. Wettability and the adhesion of the coatings were also studied. In addition, hydrogen evolution and corrosion resistance were evaluated by conducting the immersion test, electrochemical polarization, and EIS tests, respectively. The results showed that both chitosan and chitosan/ MBA composite nanocoating improved the corrosion resistance. Cytotoxicity examination using fibroblast cells indicated that the presence of MBA nanoparticles in chitosan nanofibrous coating has preferable cell adhesion and proliferation. On the whole, application of both chitosan and chitosan/ MBA nanoparticles composite nanofibrous coatings on pre-anodized magnesium appears to be a promising approach in enhancement of the corrosion and biological behavior of magnesium-based biomaterials. © 2020 Elsevier B.V.
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[1]  
Zhao D., Witte F., Lu F., Wang J., Li J., Qin L., Current status on clinical applications of magnesium-based orthopaedic implants: A review from clinical translational perspective, Biomaterials, 112, pp. 287-302, (2017)
[2]  
Julmi S., Et al., Processing and coating of open-pored absorbable magnesium-based bone implants, Mater. Sci. Eng. C, 98, pp. 1073-1086, (2019)
[3]  
Barajas J.D., Joya J.C., Duran K.S., Hernandez-Barrios C.A., Coy A.E., Viejo F., Relationship between microstructure and formation-biodegradation mechanism of fluoride conversion coatings synthesised on the AZ31 magnesium alloy, Surf. Coatings Technol, 374, pp. 424-436, (2019)
[4]  
Lu D., Huang Y., Jiang Q., Zheng M., Duan J., Hou B., An approach to fabricating protective coatings on a magnesium alloy utilising alumina, Surf. Coatings Technol, 367, pp. 336-340, (2019)
[5]  
Dezfuli S.N., Huan Z., Mol A., Leeflang S., Chang J., Zhou J., Advanced bredigite-containing magnesium-matrix composites for biodegradable bone implant applications, Mater. Sci. Eng. C, 79, pp. 647-660, (2017)
[6]  
Yazdimamaghani M., Razavi M., Vashaee D., Moharamzadeh K., Boccaccini A.R., Tayebi L., Porous magnesium-based scaffolds for tissue engineering, Mater. Sci. Eng. C, 71, pp. 1253-1266, (2017)
[7]  
Zhang G., Et al., In-situ grown super- or hydrophobic mg-Al layered double hydroxides films on the anodized magnesium alloy to improve corrosion properties, Surf. Coatings Technol, 366, pp. 238-247, (2019)
[8]  
Guo Y., Et al., Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats, Mater. Sci. Eng. C, 33, 7, pp. 4470-4474, (2013)
[9]  
Fintova S., Et al., Degradation of unconventional fluoride conversion coating on AZ61 magnesium alloy in SBF solution, Surf. Coatings Technol, 380, (2019)
[10]  
Kopp A., Et al., Influence of design and postprocessing parameters on the degradation behavior and mechanical properties of additively manufactured magnesium scaffolds, Acta Biomater., 15, pp. 23-35, (2019)
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