Gold-catalyzed formation of aryl-fused pyrazolooxazepines via intramolecular regioselective 7-exo-dig cyclization

被引：0
作者：
Guduru R. [1 ,2 ]
Mangina N.S.V.M.R. [1 ,2 ]
Sridhar B. [3 ]
Karunakar G.V. [1 ,2 ]
机构：
[1] Division of Fluoro and Agrochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad
[2] Academy of Scientific and Innovative Research, Ghaziabad
[3] Center for X-ray Crystallography, CSIR-Indian Institute of Chemical Technology, Hyderabad
来源：
Organic and Biomolecular Chemistry | 2019年 / 17卷 / 10期
关键词：
Catalysis; -; Gold;
D O I：
10.1039/C8OB03157F
中图分类号：
学科分类号：
摘要：
An efficient method was developed for the synthesis of substituted aryl-fused pyrazolooxazepines from ortho-O-propargyl aryl pyrazoles by gold catalysis. In this organic transformation a new C-N bond was formed regioselectively via 7-exo-dig cyclization. Moderate to good yields of aryl-fused pyrazolooxazepine derivatives were obtained with significant molecular complexity in one-pot. © The Royal Society of Chemistry.
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页码：2809 / 2817
页数：8
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