Emerging 0D, 1D, 2D, and 3D nanostructures for efficient point-of-care biosensing

被引：74
作者：
Byakodi M. [1 ]
Shrikrishna N.S. [1 ,2 ]
Sharma R. [1 ]
Bhansali S. [3 ]
Mishra Y. [4 ]
Kaushik A. [5 ]
Gandhi S. [1 ,2 ]
机构：
[1] DBT-National Institute of Animal Biotechnology (NIAB), Telangana, Hyderabad
[2] DBT-Regional Centre for Biotechnology (RCB), Haryana (NCR Delhi), Faridabad
[3] Department of Electrical and Computer Engineering, Florida International University, Miami, 33174, FL
[4] Mads Clausen Institute, NanoSYD, University of Southern Denmark, Alsion 2, Sønderborg
[5] NanoBioTech Laboratory, Department of Environmental Engineering, Florida Polytechnic University, Lakeland, FL
来源：
Biosensors and Bioelectronics: X | 2022年 / 12卷
关键词：
0D to 3D nanomaterials; Biosensors; Efficient diagnostics; Personalized health management; Point-of-care testing; Wearable;
D O I：
10.1016/j.biosx.2022.100284
中图分类号：
学科分类号：
摘要：
The recent COVID-19 infection outbreak has raised the demand for rapid, highly sensitive POC biosensing technology for intelligent health and wellness. In this direction, efforts are being made to explore high-performance nano-systems for developing novel sensing technologies capable of functioning at point-of-care (POC) applications for quick diagnosis, data acquisition, and disease management. A combination of nanostructures [i.e., 0D (nanoparticles & quantum dots), 1D (nanorods, nanofibers, nanopillars, & nanowires), 2D (nanosheets, nanoplates, nanopores) & 3D nanomaterials (nanocomposites and complex hierarchical structures)], biosensing prototype, and micro-electronics makes biosensing suitable for early diagnosis, detection & prevention of life-threatening diseases. However, a knowledge gap associated with the potential of 0D, 1D, 2D, and 3D nanostructures for the design and development of efficient POC sensing is yet to be explored carefully and critically. With this focus, this review highlights the latest engineered 0D, 1D, 2D, and 3D nanomaterials for developing next-generation miniaturized, portable POC biosensors development to achieve high sensitivity with potential integration with the internet of medical things (IoMT, for miniaturization and data collection, security, and sharing), artificial intelligence (AI, for desired analytics), etc. for better diagnosis and disease management at the personalized level. © 2022 The Author(s)
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