Numerical simulation of the granulation tissue resection operation in human trachea

被引：0

作者：

Zhang Z. ^{[1
]}

Jiang C. ^{[2
]}

机构：

[1] Jiangsu Key Laboratory of Special Robot Technology, College of Mechanical and Electrical Engineering, Hohai University, No. 200.Jinling North Road, Xinbei, Changzhou

[2] School of Mechanical Engineering, Changzhou University, No 1.Gehu Road, Wujin, Changzhou

来源：

MCB Molecular and Cellular Biomechanics | 2019年 / 16卷

基金：

中国国家自然科学基金;

关键词：

Computational fluid dynamics; Granulation tissue; Resection operation; Trachea;

D O I：

10.32604/mcb.2019.05749

中图分类号：

学科分类号：

摘要：

To quantitatively analyze the aerodynamic changes in patient's trachea after the resection operation of hyperplastic granulation tissue, computational fluid dynamic (CFD) method was utilized to perform the simulation. Firstly, three dimensional finite element model of the patient’s trachea before and after surgery were reconstructed based on CT images; secondly, the numerical simulation based on CFD method was performed to investigate the changes in aerodynamic changes in patient's trachea after excision. Results indicated that the dyspnea symptom was largely alleviated after the removal surgery, the abnormal morphology was obviously improved and the resistance of trachea was decreased significantly. Present research also demonstrates that CFD methods can be used to quantitatively evaluate the postoperative effects of the granulation tissue resection operation. © 2019 Tech Science Press. All rights reserved.

引用

页码：83 / 84

页数：1

共 2 条

[1] Grillo H.C., Donahue D.M., Mathisen D.J., Postintubation tracheal stenosis,treatment and results, Journal of Thoracic and Cardiovascular Surgery, 109, 3, pp. 486-492, (1995)
[2] Mukhopadhyay S., Farver F.C., Vaszar L.T., Causes of pulmonary granulomas: A retrospective study of 500 cases from seven countries, Journal of Clinical Pathology, 61, 5, pp. 51-57, (2012)

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