Medical treatment of Parkinson's disease: today and the future

被引:0
作者
Gardian, G. [1 ]
Vecsei, L. [1 ]
机构
[1] Univ Szeged, Dept Neurol, Fac Med, H-6725 Szeged, Hungary
关键词
Parkinson's disease; neuroprotection; kynurenine system; symptomatic therapy; ADENOSINE A(2A) RECEPTORS; KYNURENIC ACID; QUINOLINIC ACID; CLINICAL-EFFICACY; LEVODOPA; METABOLISM; PATHWAY; BRAIN; BLIND; NEUROPROTECTION;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Idiopathic Parkinson's disease (PD) is the only neurodegenerative disorder for which highly effective symptomatic therapy is available. Although levodopa continues to be the gold standard of symptomatic efficacy for treatment of the cardinal motor features, its chronic use is associated with potentially disabling motor complications. This review provides a survey of the medication that can currently be utilized for pharmacological management of the motor and non-motor symptoms of Parkinson's disease. Focus is placed on recent and evolving studies evaluating symptomatic and neuroprotective effects of such medication, and on how such studies may impact the future management of Parkinson's disease.
引用
收藏
页码:633 / 642
页数:10
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