Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a

被引:0
作者
Liu, Yajing [1 ,2 ,3 ]
Lou, Sensen [2 ]
Li, Jinhui [2 ]
Liu, Yuanhua [2 ]
Huang, Shisheng [1 ]
Wei, Yu [2 ]
Liu, Jikai [2 ]
Lv, Ruimin [2 ]
Tang, Junjie [2 ]
Shen, Zhixin [2 ]
Sun, Yidi [2 ]
Huang, Xingxu [1 ]
Xiong, Zhiqi [2 ]
Yang, Hui [2 ]
Zhou, Changyang [2 ]
机构
[1] Shanghai Tech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China
[2] Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techno, Shanghai Res Ctr Brain Sci & Brain Inspired Intell, Inst Neurosci,State Key Lab Neurosci,Key Lab Prima, Shanghai, Peoples R China
[3] East China Univ Sci & Technol, Shanghai, Peoples R China
基金
国家重点研发计划; 中国国家自然科学基金; 上海市科技启明星计划;
关键词
SYSTEM; ALLELE; GENE;
D O I
10.1038/s41421-024-00727-3
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页数:4
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