The Effect of Socioeconomic Status and Race/Ethnicity on the Risk of Presenting With Advanced Stage at Diagnosis in Embryonal Tumors

被引:0
作者
Jung, Eun Mi [1 ]
Kitlinska, Joanna B. [2 ]
Johnson, Rebecca A. [1 ]
Spector, Logan G. [1 ,3 ]
机构
[1] Univ Minnesota, Dept Pediat, Div Epidemiol & Clin Res, Minneapolis, MN USA
[2] Georgetown Univ, Med Ctr, Dept Biochem & Mol & Cellular Biol, Washington, DC USA
[3] Univ Minnesota, Masonic Canc Ctr, Minneapolis, MN USA
关键词
embryonal tumors; incidence; socioeconomic status; race; ethnicity; metastases; HEALTH DISPARITIES; CHILDHOOD-CANCER; UNITED-STATES; CHILDREN; SYSTEM; CLASSIFICATION; DETERMINANTS; POPULATION; SURVIVAL; OUTCOMES;
D O I
10.1097/MPH.0000000000002860
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We evaluated whether socioeconomic status (SES), race/ethnicity, and their interaction were associated with the presentation of advanced stage at diagnosis in embryonal tumors. Children 0 to 19 years of age diagnosed with embryonal tumors between 2006 and 2018 were identified from the US Surveillance, Epidemiology, and End Results program database specialized with Census Tract SES/Rurality. SES quintile was derived from a composite index for census tracts. We performed logistic regression to estimate odds ratios (ORs) and 95% confidence intervals by SES and race/ethnicity, adjusting for sex, age, and diagnosis year. Overall, no significant associations were found between either SES or race/ethnicity and the risk of presenting with advanced stage at diagnosis, although patterns of risk reductions were observed in atypical teratoid/rhabdoid tumors and embryonal rhabdomyosarcoma with increasing SES. In the stratified analysis, decreased odds of presenting with advanced-stage embryonal rhabdomyosarcoma were observed for Hispanics with higher SES (OR: 0.24, 95% Confidence Interval: 0.08-0.75) compared with Hispanics with lower SES. Future studies incorporating individual-level SES, cancer-specific staging information, and potential demographic, clinical, epidemiological, and genetic risk factors are warranted to confirm our findings.
引用
收藏
页码:e259 / e264
页数:6
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