Systemic immune-inflammation and prognostic immune nutritional index in oral squamous cell carcinoma patients

被引：0
作者：
Li, Zhenzhen [1 ]
Ge, Shaowen [1 ]
Song, Chi [1 ]
Li, Yaning [2 ]
Xie, Xiaofei [2 ]
Xu, Li [2 ]
Liao, Shengkai [1 ]
Zhang, Kai [1 ]
机构：
[1] Bengbu Med Coll, Affiliated Hosp 1, Dept Stomatol, Bengbu, Peoples R China
[2] Bengbu Med Univ, Affiliated Hosp 1, Dept Ultrasound, Bengbu, Peoples R China
来源：
BIOMARKERS IN MEDICINE | 2024年 / 18卷 / 17-18期
关键词：
malnutrition; oral squamous cell carcinoma (OSCC); prognostic immune nutritional index; prognostic value; systemic immune-inflammation index; CANCER; NEUTROPHILS;
D O I：
10.1080/17520363.2024.2394390
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Aim: To investigate the systemic immune-inflammation index and prognostic immune nutritional index in the prognostic evaluation of oral squamous cell carcinoma. Materials & methods: We analyzed retrospectively the relationship between systemic immune-inflammation index, prognostic immune nutritional index and clinicopathological variables and the overall survival of 262 patients who underwent radical surgery. Results: Multivariate analysis showed high systemic immune-inflammation index (Hazard ratio = 3.062, 95% CI: 1.021-8.251), low prognostic immune nutritional index (Hazard ratio = 0.297, 95% CI: 0.139-0.636), tumor node metastasis classification 3-4 (Hazard ratio = 9.862, 95% CI: 4.658-20.880) patients have worse overall survival. Conclusion: Preoperative systemic immune-inflammation index and prognostic immune nutritional index are independent risk factors for prognostic survival status in oral squamous cell carcinoma.
引用
收藏
页码：759 / 770
页数：12
相关论文
共 45 条
[1]   Biomarkers for Immunotherapy of Oral Squamous Cell Carcinoma: Current Status and Challenges [J].
Almangush, Alhadi ;
Leivo, Ilmo ;
Makitie, Antti A. .
FRONTIERS IN ONCOLOGY, 2021, 11
[2]   Nutritional risk and malnutrition rates at diagnosis of cancer in patients treated in outpatient settings: Early intervention protocol [J].
Alvaro Sanz, Elena ;
Garrido Siles, Marga ;
Rey Fernandez, Laura ;
Villatoro Roldan, Rosa ;
Rueda Dominguez, Antonio ;
Abiles, Jimena .
NUTRITION, 2019, 57 :148-153
[3]   A meta-analysis of margin size and local recurrence in oral squamous cell carcinoma [J].
Anderson, Caroline Rachael ;
Sisson, Katherine ;
Moncrieff, Marc .
ORAL ONCOLOGY, 2015, 51 (05) :464-469
[4]   Nutritional assessment and prognosis of oral cancer patients: a large-scale prospective study [J].
Bao, Xiaodan ;
Liu, Fengqiong ;
Lin, Jing ;
Chen, Qing ;
Chen, Lin ;
Chen, Fa ;
Wang, Jing ;
Qiu, Yu ;
Shi, Bin ;
Pan, Lizhen ;
Lin, Lisong ;
He, Baochang .
BMC CANCER, 2020, 20 (01)
[5]   Tumor-Educated Platelets as a Noninvasive Biomarker Source for Cancer Detection and Progression Monitoring [J].
Best, Myron G. ;
Wesseling, Pieter ;
Wurdinger, Thomas .
CANCER RESEARCH, 2018, 78 (13) :3407-3412
[6]   Survival after curative surgical treatment for primary oral squamous cell carcinoma [J].
Bloebaum, M. ;
Poort, L. ;
Bockmann, R. ;
Kessler, P. .
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 2014, 42 (08) :1572-1576
[7]   Baseline neutrophil-to-lymphocyte ratio (NLR) and derived NLR could predict overall survival in patients with advanced melanoma treated with nivolumab [J].
Capone, Mariaelena ;
Giannarelli, Diana ;
Mallardo, Domenico ;
Madonna, Gabriele ;
Festino, Lucia ;
Grimaldi, Antonio Maria ;
Vanella, Vito ;
Simeone, Ester ;
Paone, Miriam ;
Palmieri, Giuseppe ;
Cavalcanti, Ernesta ;
Caraco, Corrado ;
Ascierto, Paolo Antonio .
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2018, 6
[8]   Systemic immune-inflammation index for predicting prognosis of colorectal cancer [J].
Chen, Jian-Hui ;
Zhai, Er-Tao ;
Yuan, Yu-Jie ;
Wu, Kai-Ming ;
Xu, Jian-Bo ;
Peng, Jian-Jun ;
Chen, Chuang-Qi ;
He, Yu-Long ;
Cai, Shi-Rong .
WORLD JOURNAL OF GASTROENTEROLOGY, 2017, 23 (34) :6261-6272
[9]   Long noncoding RNA lnc-H2AFV-1 promotes cell growth by regulating aberrant m6A RNA modification in head and neck squamous cell carcinoma [J].
Chen, Xi ;
Liu, Yunxia ;
Sun, Dongyuan ;
Sun, Rongqi ;
Wang, Xiaoxiao ;
Li, Minmin ;
Song, Ning ;
Ying, Jicheng ;
Guo, Tao ;
Jiang, Yingying .
CANCER SCIENCE, 2022, 113 (06) :2071-2084
[10]   Evaluation of sarcopenia as a prognostic biomarker in locally advanced head and neck squamous cell carcinoma [J].
Erul, Enes ;
Guven, Deniz C. ;
Ozbay, Yakup ;
Altunbulak, Ahmet Y. ;
Kahvecioglu, Alper ;
Ercan, Fatih ;
Yesil, Muhammed F. ;
Ucdal, Mete T. ;
Cengiz, Mustafa ;
Yazici, Gozde ;
Kuscu, Oguz ;
Suslu, Nilda ;
Gullu, Ibrahim ;
Onur, Mehmet R. ;
Aksoy, Sercan .
BIOMARKERS IN MEDICINE, 2023, 17 (02) :87-99
12345