Chronic thromboembolic pulmonary hypertension: the diagnostic assessment

被引:0
作者
Simeone, Beatrice [1 ]
Maggio, Enrico [2 ]
Schirone, Leonardo [3 ]
Rocco, Erica [1 ]
Sarto, Gianmarco [1 ]
Spadafora, Luigi [1 ]
Bernardi, Marco [1 ]
D'Ambrosio, Luca [4 ]
Forte, Maurizio [3 ]
Vecchio, Daniele [4 ]
Valenti, Valentina [5 ,6 ]
Sciarretta, Sebastiano [3 ,4 ]
Vizza, Carmine Dario [7 ]
机构
[1] ICOT Ist Marco Pasquali, Dept Cardiol, Latina, Italy
[2] Sapienza Univ Rome, Dept Clin Internal Anesthesiol & Cardiovasc Sci, Rome, Italy
[3] IRCCS Neuromed, Dept Angiocardioneurol, Pozzilli, Italy
[4] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, Latina, Italy
[5] St Maria Goretti Hosp, Dept Cardiol, Latina, Italy
[6] Maria Cecilia Hosp, GVM Care & Res, Dept Cardiol, Cotignola, Italy
[7] Sapienza Univ Rome, Dept Cardiovasc & Resp Sci, Rome, Italy
来源
FRONTIERS IN CARDIOVASCULAR MEDICINE | 2024年 / 11卷
关键词
pulmonary hypertension; chronic thromboembolic pulmonary hypertension (CTEPH); rare disease; diagnosis; narrative review; RIGHT HEART CATHETERIZATION; ARTERIAL-PRESSURE; SCAN FINDINGS; RISK-FACTORS; EXERCISE; PERFUSION; ECHOCARDIOGRAPHY; MANAGEMENT; FAILURE; COMPLICATIONS;
D O I
10.3389/fcvm.2024.1439402
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) presents a significant diagnostic challenge due to its complex and often nonspecific clinical manifestations. This review outlines a comprehensive approach to the diagnostic assessment of CTEPH, emphasizing the importance of a high index of suspicion in patients with unexplained dyspnea or persistent symptoms post-acute pulmonary embolism. We discuss the pivotal role of multimodal imaging, including echocardiography, ventilation/perfusion scans, CT pulmonary angiography, and magnetic resonance imaging, in the identification and confirmation of CTEPH. Furthermore, the review highlights the essential function of right heart catheterization in validating the hemodynamic parameters indicative of CTEPH, establishing its definitive diagnosis. Advances in diagnostic technologies and the integration of a multidisciplinary approach are critical for the timely and accurate diagnosis of CTEPH, facilitating early therapeutic intervention and improving patient outcomes. This manuscript aims to equip clinicians with the knowledge and tools necessary for the efficient diagnostic workflow of CTEPH, promoting awareness and understanding of this potentially treatable cause of pulmonary hypertension.
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页数:17
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