Oral Health and "Modern" Digestive Diseases: Pathophysiologic and Etiologic Factors

被引：0

作者：

Rotaru, Mihaela ^{[1
]}

Singeap, Ana-Maria ^{[2
,3
,4
]}

Ciobica, Alin ^{[1
,4
,5
,6
]}

Huiban, Laura ^{[2
,3
]}

Stanciu, Carol ^{[2
,3
,5
,6
]}

Romila, Laura ^{[7
]}

Burlui, Vasile ^{[7
]}

Mavroudis, Ioannis ^{[8
,9
]}

Trifan, Anca ^{[2
,3
,4
]}

机构：

[1] Alexandru Ioan Cuza Univ, Fac Biol, Dept Biol, Bd Carol I 20A, Iasi 700505, Romania

[2] Grigore T Popa Univ Med & Pharm, Fac Med, Dept Gastroenterol, Univ St 16, Iasi 700115, Romania

[3] St Spiridon Emergency Cty Hosp, Inst Gastroenterol & Hepatol, Bd Independentei 1, Iasi 700111, Romania

[4] Grigore T Popa Univ Med & Pharm, CENEMED Platform Interdisciplinary Res, Univ St 16, Iasi 700115, Romania

[5] Romanian Acad, Ctr Biomed Res, Bd Carol I 8, Iasi 700506, Romania

[6] Acad Romanian Scientists, Splaiul Independentei St 54, Bucharest 050094, Romania

[7] Apollonia Univ, Ioan Haul Inst, Pacurari St 11, Iasi 700511, Romania

[8] Leeds Teaching Hosp NHS Trust, Dept Neurosci, Leeds LS2 9JT, England

[9] Aristotle Univ Thessaloniki, Dept Neurol 3, Thessaloniki 54124, Greece

来源：

BIOMEDICINES | 2024年 / 12卷 / 08期

关键词：

irritable bowel syndrome; intestinal dysbiosis; inflammatory bowel disease; oral diseases; small intestinal bacterial overgrowth; non-alcoholic fatty liver disease; INFLAMMATORY-BOWEL-DISEASE; FATTY LIVER-DISEASE; INTESTINAL BACTERIAL OVERGROWTH; PERIODONTAL-DISEASE; DENTAL-CARIES; PREVALENCE; MICROBIOTA; MANIFESTATIONS; SYMPTOMS; CRITERIA;

D O I：

10.3390/biomedicines12081854

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In the contemporary era of medicine, exploring the complexity of the human body and its intricate interactions has become a central concern for health researchers. The main purpose of this article is to summarize the current understanding of relevant pathophysiological factors such as chronic inflammation, dysbiosis (microbial imbalance), and metabolic disorders, as well as etiological factors including dietary habits, lifestyle choices, obesity, metabolic syndrome, and genetic predispositions, as well as to emphasize potential avenues for upcoming studies and their medical significance. Additionally, this article aims to assess the potential impact of integrated treatment approaches on patient outcomes, emphasizing the need for interdisciplinary collaboration between gastroenterologists, dentists, and other healthcare professionals to develop comprehensive care plans that address both oral and digestive health issues simultaneously. Among the branches with a significant impact on general well-being are oral cavity health and digestive diseases, which have been the subject of intensive research in recent decades. In this context, analysis of the current state of knowledge on oral cavity disorders in relation to "modern" digestive diseases such as non-alcoholic fatty liver disease (NAFLD), small intestinal bacterial overgrowth (SIBO), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS) becomes essential for a deeper understanding of the interconnections between oral and digestive health. The temporal overlap or succession, whether preceding or following, of oral manifestations and digestive disorders should be taken seriously by both gastroenterologists and dentists to facilitate early diagnosis and explain to patients the correlation between these two body systems. In summary, this article underscores the importance of understanding the intricate relationship between oral and digestive health, advocating for interdisciplinary approaches to improve patient outcomes and guide future research.

引用

页数：19