Electrochemical detection of folic acid in food extracts using molecularly imprinted polyacrylonitrile imbued graphite electrode

被引:2
作者
Bandyopadhyay, Dipan [1 ]
Nag, Shreya [2 ]
Das, Debangana [3 ]
Roy, Runu Banerjee [1 ]
机构
[1] Jadavpur Univ, Dept Instrumentat & Elect Engn, Salt Lake Campus,Block LB,Sect 3,Plot 8, Kolkata 700106, India
[2] Univ Engn & Management, Kolkata 700160, India
[3] Silicon Inst Technol, Dept Elect & Commun Engn, Bhubaneswar 751024, Odisha, India
关键词
Folic acid (FA); Molecularly imprinted polymer (MIP); Cyclic voltammetry; Electrochemical detection; HPLC; HPLC DETERMINATION; METHOTREXATE; NANOPARTICLES; POLYMERS;
D O I
10.1016/j.aca.2024.343120
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The present study elucidates the effectiveness of a molecularly imprinted polyacrylonitrile-imbued graphite-base electrode (MAN@G) for the selective detection of folic acid (FA) in food samples. The prime objective of the recognition and quantification of vitamin compounds like FA is the overall quality assessment of vegetables and fruits. The cost-effective, reproducible, and durable MAN@G electrode has been fabricated using acrylonitrile (AN) as the monomer and FA as the template over graphite-base. The characterization of the synthesized MAN@G electrode material has been accomplished by utilizing UV-visible (UV-vis) spectroscopy and scanning electron microscopy (SEM). A tri-electrode system based on differential pulse voltammetry (DPV) and cyclic voltammetry (CV) techniques was employed to explore the analytical performance of the synthesized electrode. Rigorous analyses divulged that a widespread linearity window could be exhibited by the electrode under an optimized experimental environment, ranging from 20 mu M to 400 mu M concentrations with an acceptable lower limit of detection (LOD) and limit of quantification (LOQ) of 18 nM, and 60 nM respectively. Additionally, this
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页数:9
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