Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration in a Paediatric Population: A Single-Centre Experience

被引:0
|
作者
Bashir, Shaarif [1 ]
Loya, Asif [1 ]
Hussain, Mudassar [1 ]
Sheikh, Umer Nisar [1 ]
Maqbool, Hina [1 ]
Yusuf, Muhammed Aasim [2 ]
机构
[1] Shaukat Khanum Mem Canc Hosp & Res Ctr, Dept Pathol, Lahore, Pakistan
[2] Shaukat Khanum Mem Canc Hosp & Res Ctr, Dept Internal Med, Lahore, Pakistan
关键词
Endoscopic ultrasound-guided fine-needle aspiration; Paediatric patients; Cytopathology; ON-SITE EVALUATION; EUS-FNA; CYTOPATHOLOGY EVALUATION; CARE; ULTRASONOGRAPHY; COMPLICATIONS; DIAGNOSIS; PANCREAS; BIOPSY; IMPACT;
D O I
10.1159/000541140
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Introduction: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a modern and minimally invasive technique to acquire diagnostic material from within the gastrointestinal tract, as well as from adjacent organs and structures, which can help in the diagnosis and staging of a variety of gastrointestinal malignancies, as well as for non-malignant conditions. Though well described in adults, there is limited literature on the diagnostic utility of EUS-FNA in paediatric patients. The objective of this study was to evaluate the diagnostic accuracy and clinical utility of EUS-FNA in paediatric patients performed at our centre over the last 17 years. Materials and Methods: After obtaining Institutional Review Board approval, 63 cases of paediatric EUS-FNA performed at SKMCH&RC from 2005 to 2022 were retrieved. A 22-gauge EUS-FNA needle was used for obtaining samples with the use of suction (when required). The sample was then smeared onto glass slides, with half being stained with RAPI stain while the rest with the Papanicolaou stain. Demographic details, indication for the procedure, results of rapid on-site adequacy status (ROSE), site of lesion, and cytological diagnosis were reviewed and analysed. Results: Of the 63 patients, 55 (87.3%) had an adequate sample (confirmed on ROSE). Forty-two (66.7%) were male and the mean age was 12.4 years. The most frequent indication of EUS-FNA was a sampling of enlarged lymph nodes (74.6%). The most common sites of nodal aspiration were sub-carinal (33.3%) and celiac lymph nodes (14.3%). EUS-FNA of a pancreatic lesion accounted for an additional 17.5% of cases. Involvement by Hodgkin's lymphoma was the most common diagnosis (25.4%) followed by granulomatous inflammation (19.1%). Cases of solid pseudo-papillary tumour (4.8%) and recurrent Wilm's tumour (3.2%) were also diagnosed. No patient suffered complications, and none required hospital admission, post-procedure. The sensitivity, specificity, PPV, and NPV of EUS-FNA were 98.1, 83.3, 96.4, and 90.9%, respectively. Conclusion: EUS-FNA is a safe, well-tolerated, minimally invasive outpatient setting procedure with high sensitivity and significant utility in the diagnosis and staging of disease.
引用
收藏
页码:397 / 404
页数:8
相关论文
共 50 条
  • [1] ENDOSCOPIC ULTRASOUND-GUIDED FINE-NEEDLE ASPIRATION
    CHANG, KJ
    KATZ, KD
    DURBIN, TE
    ERICKSON, RA
    BUTLER, JA
    LIN, F
    WUERKER, RB
    GASTROINTESTINAL ENDOSCOPY, 1994, 40 (06) : 694 - 699
  • [2] Endoscopic ultrasound-guided fine-needle aspiration
    Eloubeidi, MA
    Vilmann, P
    Wiersema, MJ
    ENDOSCOPY, 2004, 36 (10) : 901 - 908
  • [3] Endoscopic ultrasound-guided fine-needle aspiration
    Schanz, S
    Kruis, W
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2005, 130 (34-35) : 1957 - 1961
  • [4] Endoscopic ultrasound-guided fine-needle aspiration
    Stanley, MW
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2003, 120 (03) : 309 - 310
  • [5] Risks of Endoscopic Ultrasound and Endoscopic Ultrasound-Guided Fine-Needle Aspiration
    Ho, Sammy
    TECHNIQUES IN GASTROINTESTINAL ENDOSCOPY, 2008, 10 (01) : 22 - 24
  • [6] Endoscopic ultrasound-guided fine-needle aspiration of ascites
    DeWitt, John
    LeBlanc, Julia
    McHenry, Lee
    McGreevy, Kathy
    Sherman, Stuart
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2007, 5 (05) : 609 - 615
  • [7] A Meta-Analysis Comparing Endoscopic Ultrasound-guided Fine-needle Aspiration With Endoscopic Ultrasound-guided Fine-needle Biopsy
    Li, Zhiwang
    Liu, Wei
    Xu, Xiaoda
    Li, Peiyu
    JOURNAL OF CLINICAL GASTROENTEROLOGY, 2022, 56 (08) : 668 - 678
  • [8] Utility of Ultrasound-Guided Fine-Needle Aspiration in Splenic Lesions
    Handa, Uma
    Tiwari, Avani
    Singhal, Niti
    Mohan, Harsh
    Kaur, Ravinder
    DIAGNOSTIC CYTOPATHOLOGY, 2013, 41 (12) : 1038 - 1042
  • [9] Role of endoscopic ultrasound-guided fine needle aspiration and ultrasound-guided fine-needle aspiration in diagnosis of cystic pancreatic lesions
    Okasha, Hussein Hassan
    Ashry, Mahmoud
    Imam, Hala M. K.
    Ezzat, Reem
    Naguib, Mohamed
    Farag, Ali H.
    Gemeie, Emad H.
    Khattab, Hani M.
    ENDOSCOPIC ULTRASOUND, 2015, 4 (02) : 132 - 136
  • [10] Clinical utility of endoscopic ultrasound-guided fine needle aspiration
    Erickson, RA
    SayageRabie, L
    AvotsAvotins, A
    ACTA CYTOLOGICA, 1997, 41 (06) : 1647 - 1653