Modern Perspective of Lactate Metabolism

被引:2
|
作者
Vavricka, Jakub [1 ]
Broz, Pavel [1 ,2 ]
Follprecht, Daniel [1 ]
Novak, Jaroslav [1 ]
Krouzecky, Ales [1 ]
机构
[1] Charles Univ Prague, Fac Med Pilsen, Dept Sports Med & Act Hlth Sci, Alej Svobody76, Plzen 32300, Czech Republic
[2] Univ Hosp Plzen, Inst Clin Biochem & Hematol, Plzen, Czech Republic
关键词
Lactate; Lactate metabolism; Lactic acid; Disease metabolism; Lactate shuttle; TRAUMATIC BRAIN-INJURY; IN-VIVO EVIDENCE; ENERGY-METABOLISM; BLOOD LACTATE; LACTIC-ACID; EXERCISE; GLUCOSE; MITOCHONDRIAL; OXIDATION; MEMBRANE;
D O I
10.33549/physiolres.935331
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Once considered a metabolic waste product, today it is considered an important signaling molecule continuously forming under aerobic conditions. Lactate, a molecule primarily known as a byproduct of glycolysis, has gained importance in recent years due to its multifaceted role in various biological processes. Misconceptions surrounding lactate have persisted for centuries, especially the belief that elevated lactate levels were solely a result of low oxygen levels shaped early understanding. However, current research challenges this view and expands our comprehension of lactate's various roles. Unfortunately, despite all of the mentioned above lactate is rooted in modern society as a deterrent word and many people do not know its value in the human body, let alone clinical implementations or physical information among a professional society.
引用
收藏
页码:499 / 514
页数:16
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