Surgical Management of Hereditary Gingival Fibromatosis: Case Series

被引:0
作者
Shadab, Hassina [1 ]
Nawabi, Aisha [1 ]
Anwari, Abdurrahman [2 ]
Nejabi, Mohammad Bashir [3 ]
Ghafari, Elaha Somaya [1 ]
Karimi, Sajeya [1 ]
Ahmadi, Mohammad Eissa [1 ]
机构
[1] Kabul Univ Med Sci KUMS, Periodont Dept, Kabul, Afghanistan
[2] Kabul Univ Med Sci KUMS, Operat Restorat Dent & Endodont Dept, Kabul, Afghanistan
[3] Kabul Univ Med Sci KUMS, Prosthodont Dept, Kabul, Afghanistan
来源
CLINICAL COSMETIC AND INVESTIGATIONAL DENTISTRY | 2024年 / 16卷
关键词
hereditary gingival fibromatosis; gingivectomy; osteoplasty; gingival enlargement; case series; HISTOMORPHOMETRIC CHARACTERISTICS;
D O I
10.2147/CCIDE.S480490
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Hereditary gingival fibromatosis (HGF) is an uncommon genetic condition marked by gradual and progressive overgrowth of fibrous tissue in the gums, which is benign in nature. It is a genetic disorder inherited in an autosomal dominant pattern, known for its considerable genetic diversity. The marginal, attached, and interdental gingivae are affected by this condition. The affected area appears pink, does not bleed easily, and exhibits a firm, fibrotic texture. Additionally, it displays a hard, widespread nodular growth that is smooth to stippled and has little bleeding tendency. Nevertheless, in certain instances, the enlargement may feel so dense and firm that it resembles bone upon palpation. Accordingly, esthetics and functions related to a healthy gingiva is also affected. The choice of treatment modality often depends on factors such as the severity of gingival overgrowth, available resources, and patient- specific considerations. Laser techniques and electrosurgery have emerged as valuable options, providing benefits like reduced discomfort and enhanced precision. However, traditional surgical methods remain highly effective, particularly when advanced technologies are not available. This article reports on three cases of hereditary gingival fibromatosis (HGF) treated with conventional gingivectomy, flap procedures, and resective osseous surgery (osteoplasty and osteotomy). The aim is to support the efficacy of these interventions in addressing patient complaints and preparing the groundwork for managing additional issues, such as speech and mastication difficulties, delayed eruption of permanent teeth, and malocclusion. The surgical treatment led to significant improvements: masticatory function was markedly enhanced, aesthetic outcomes were notably better, and oral hygiene significantly improved. Additionally, the procedures created favorable conditions for future treatments, including orthodontics, implants, or prosthetics, by providing a more manageable and functional oral environment.
引用
收藏
页码:307 / 319
页数:13
相关论文
共 34 条
  • [1] Aboujaoude Samia, 2022, Cureus, V14, pe23280, DOI 10.7759/cureus.23280
  • [2] Hereditary Gingival Fibromatosis and Developmental Anomalies: A Case Report
    Afonso, Rhaina A.
    Godinho, Gessica, V
    Silva, Cristhiane A.
    Silva, Everton J.
    Volpato, Luiz E.
    [J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (04)
  • [3] Gingival enlargements: Differential diagnosis and review of literature
    Agrawal, Amit Arvind
    [J]. WORLD JOURNAL OF CLINICAL CASES, 2015, 3 (09) : 779 - 788
  • [4] Alminana-Pastor Pedro J, 2017, J Clin Exp Dent, V9, pe599, DOI 10.4317/jced.53644
  • [5] ANAVI Y, 1989, DEV MED CHILD NEUROL, V31, P538
  • [6] Histomorphometric characteristics and expression of epidermal growth factor and its receptor by epithelial cells of normal gingiva and hereditary gingival fibromatosis
    Araujo, CSA
    Graner, E
    Almeida, OP
    Sauk, JJ
    Coletta, RD
    [J]. JOURNAL OF PERIODONTAL RESEARCH, 2003, 38 (03) : 237 - 241
  • [7] Hereditary gingival fibromatosis: a case report
    Baptista, IP
    [J]. JOURNAL OF CLINICAL PERIODONTOLOGY, 2002, 29 (09) : 871 - 874
  • [8] REST Final-Exon-Truncating Mutations Cause Hereditary Gingival Fibromatosis
    Bayram, Yavuz
    White, Janson J.
    Elcioglu, Nursel
    Cho, Megan T.
    Zadeh, Neda
    Gedikbasi, Asuman
    Palanduz, Sukru
    Ozturk, Sukru
    Cefle, Kivanc
    Kasapcopur, Ozgur
    Akdemir, Zeynep Coban
    Pehlivan, Davut
    Begtrup, Amber
    Carvalho, Claudia M. B.
    Paine, Ingrid Sophie
    Mentes, Ali
    Bektas-Kayhan, Kivanc
    Karaca, Ender
    Jhangiani, Shalini N.
    Muzny, Donna M.
    Gibbs, Richard A.
    Lupski, James R.
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2017, 101 (01) : 149 - 156
  • [9] Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism
    Bhowmick, NA
    Ghiassi, M
    Bakin, A
    Aakre, M
    Lundquist, CA
    Engel, ME
    Arteaga, CL
    Moses, HL
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (01) : 27 - 36
  • [10] Hereditary gingival fibromatosis in children: a systematic review of the literature
    Boutiou, Eirini
    Ziogas, Ioannis A.
    Giannis, Dimitrios
    Doufexi, Aikaterini-Elisavet
    [J]. CLINICAL ORAL INVESTIGATIONS, 2021, 25 (06) : 3599 - 3607