Stereochemical effects of chiral monolayers on enhancing the resistance to mammalian cell adhesion

被引:20
作者
Bandyopadhyay, Debjyoti [1 ]
Prashar, Deepali [1 ]
Luk, Yan-Yeung [1 ]
机构
[1] Syracuse Univ, Dept Chem, Dept Biomed Engn, Syracuse, NY 13244 USA
基金
美国国家科学基金会;
关键词
SELF-ASSEMBLED MONOLAYERS; AQUEOUS GUANIDINE-HYDROCHLORIDE; BOVINE SERUM-ALBUMIN; PROTEIN ADSORPTION; OLIGO(ETHYLENE GLYCOL); MOLECULAR-CONFORMATION; HOFMEISTER SERIES; BIOFILM FORMATION; CRYSTAL-SURFACES; GOLD;
D O I
10.1039/c1cc10855g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This work describes the different durations of surface confinement of adhered mammalian cells by monolayers comprised of enantiomers of bio-inert polyol-terminated alkanethiols. Enhanced resistance to protein adsorption and cell adhesion is obtained on monolayers formed by a racemic mixture of the enantiomeric alkanethiols.
引用
收藏
页码:6165 / 6167
页数:3
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