The role of mitochondrial fusion and fission in immune-mediated inflammatory diseases

被引：0
|
作者：
Fang, Yulai [1 ,2 ]
Min, Shichen [1 ]
Shen, Hong [1 ,2 ]
机构：
[1] Nanjing Univ Chinese Med, Affiliated Hosp, Nanjing 210029, Peoples R China
[2] Jiangsu Prov Hosp Tradit Chinese Med, Nanjing 210029, Peoples R China
来源：
CELLULAR IMMUNOLOGY | 2024年 / 403卷
关键词：
Mitochondrial fusion; Mitochondrial fission; Immune-mediated inflammatory diseases; DYNAMICS; PHOSPHORYLATION; INHIBITION;
D O I：
10.1016/j.cellimm.2024.104864
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Mitochondria are highly dynamic organelles that maintain their homeostasis through mitochondrial dynamics. Mitochondrial fusion and fission are two important processes of mitochondrial dynamics. There is accumulating evidence that mitochondrial fusion and fission play an important role in the development of immune-mediated inflammatory diseases. This article provides a brief review of the essential role of mitochondrial fusion and fission in immune-mediated inflammatory diseases. It will provide a novel perspective and direction for the elucidation of the pathogenesis and treatment of immune-mediated inflammatory diseases.
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页数：6
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