Black tea extracts enhance stress-induced sleep of Caenorhabditis elegans to resist UV damage

被引：1

作者：

Chen, Ying ^{[1
,2
]}

Ouyang, Jin ^{[1
,2
]}

Tang, Xiangyue ^{[2
,3
]}

Tong, Jiewen ^{[5
]}

Liu, He ^{[6
]}

Liu, Zhonghua ^{[3
,4
]}

Gong, Yushun ^{[1
]}

机构：

[1] Minist Educ, Key Lab Tea Sci, Changsha 410128, Peoples R China

[2] Natl Res Ctr Engn & Technol Utilizat Bot Funct Ing, Changsha 410128, Peoples R China

[3] Educ Minist Utilizat Bot Funct Ingredients, Coinnovat Ctr, Changsha 410128, Peoples R China

[4] Hunan Agr Univ, Key Lab Evaluat & Utilizat Gene Resources Hort Cro, Minist Agr & Rural Affairs China, Changsha 410128, Peoples R China

[5] Xinyang Agr & Forestry Univ, Coll Tea Sci, Xinyang 464000, Peoples R China

[6] Beijing Normal Univ, Fac Arts & Sci, Dept Syst Sci, Zhuhai 519087, Guangdong, Peoples R China

来源：

FOOD RESEARCH INTERNATIONAL | 2024年 / 196卷

关键词：

Lifespan; UV-stress; Resting; Lipid; Black tea; Theaflavins; ULTRAVIOLET-LIGHT; QUIESCENCE; DOPAMINE; STATE;

D O I：

10.1016/j.foodres.2024.115025

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Black tea is believed to strengthen the ability of the body to defend itself against external stimuli. Here, by examining Caenorhabditis elegans (C. elegans) locomotor behavior over a short period after UV stress, we found that feeding black tea extract (BTE) caused worms to enter a superior stress-induced sleep (SIS) state, which potentially boosting organismal recovery. BTE enhances SIS through KIN-29 mediated epidermal growth factor signaling and modulation of sleep by specific interneurons ALA and RIS. It also inhibits lipid degradation during sleep. These functions were also observed when theaflavins (TFs) were fed. In conclusion, our results describe a new way for BTE-enhanced damage repair in C. elegans after UV stress that relies on enhanced SIS, and confirm the contribution of TFs therein.

引用

页数：9

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