In terms of road safety, motorways offer much better records as compared to other road types. In EU, motorways represent an approximately 10% of all paved road network. Greece had until recently a significantly lower percentage of motorways, but during the last 15 years this percentage has been sharply increased to approach the EU average. The present paper provides a comparative analysis of motorways' safety between Greece and EU, using certain safety indicators, mainly fatality rates. The analysis is particularly concentrated in similar to Greece EU countries. Overall, Greek road safety records are traditionally poor compared to other EU countries, due to drivers' aggressive driving as the main reason. However, safety records in Greek motorways are comparable to those of EU motorways, hence the many km of newly constructed motorways in Greece have been contributed to improve country's safety indices.