Exosomes in Renal Cell Cancer: Diagnostic and Therapeutic Nanovehicles

被引：2

作者：

Boussios, Stergios ^{[1
,2
,3
,4
,5
]}

Ovsepian, Saak V. ^{[6
,7
]}

机构：

[1] Medway NHS Fdn Trust, Dept Med Oncol, Gillingham, England

[2] Canterbury Christ Church Univ, Fac Med Hlth & Social Care, Canterbury CT2 7PB, England

[3] Kings Coll London, Fac Life Sci & Med, Sch Canc & Pharmaceut Sci, London WC2 R2LS, England

[4] Univ Kent, Kent & Medway Med Sch, Canterbury CT2 7LX, Kent, England

[5] AELIA Org, Thessaloniki, Greece

[6] Univ Greenwich London, Fac Engn & Sci, Chatham, Kent, England

[7] Tbilisi State Med Univ, Fac Med, Tbilisi, Georgia

来源：

TECHNOLOGY IN CANCER RESEARCH & TREATMENT | 2024年 / 23卷

关键词：

Exosomes; renal cancer; tumor microenvironment; extracellular vesicles; biomarker;

D O I：

10.1177/15330338241275403

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Early diagnosis is crucial for enhancing the survival rate of renal cell cancer patients, and exosomes present potential advantages in this area. Their small size, high mobility, and lipid bilayer structure enable exosomes to cross biological membranes easily, protecting the bioactive cargo within from degradation. Exosomes significantly influence the invasion and metastasis of RCC, and they also contribute to tumor drug resistance and immune evasion.

引用

页数：4

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