Electrochemical Carboarylation of Activated Alkenes with CO2 and Electron-deficient Aryl Bromides

被引：5

作者：

Yang, Zhaoliang ^{[1
]}

Liu, Chunlei ^{[1
]}

Zhong, Cheng ^{[1
]}

Zhang, Jianye ^{[1
]}

Liu, Shengzhang ^{[3
]}

Yu, Mingming ^{[4
]}

Li, Yangyang ^{[2
]}

Yi, Hong ^{[2
]}

Lei, Aiwen ^{[1
,2
]}

机构：

[1] Jiangxi Normal Univ, Natl Engn Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China

[2] Wuhan Univ, Inst Adv Studies IAS, Coll Chem & Mol Sci, Wuhan 430072, Hubei, Peoples R China

[3] Jiangxi Univ Chinese Med, Sch Pharm, Nanchang 330004, Jiangxi, Peoples R China

[4] Zhejiang Sci Tech Univ, Sch Chem & Chem Engn, Xiasha West Higher Educ Dist, Hangzhou 310018, Zhejiang, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2024年 / 42卷 / 24期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

Electroreductive; Difunctionalization; Carboarylation; Activated alkenes; CO2; Aryl bromides; CARBON-DIOXIDE; DIAZONIUM SALTS; PHOTOREDOX; ARYLATION; STYRENES; HYDROCARBOXYLATION; ELECTROSYNTHESIS; GOLD; IRON;

D O I：

10.1002/cjoc.202400661

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The simultaneous construction of two vicinal C-C bonds in a molecule remains a significant challenge. In this work, we disclose an electroreductive carboarylation of activated alkenes under mild, transition metal-free conditions. Utilizing readily available starting materials (electron-deficient aryl bromides, activated alkenes, and CO2), this method demonstrates broad substrate scope and good functional group tolerance. Notably, this strategy enables the addition of two distinct electrophiles across an alkene in a highly chemo- and regioselective manner.

引用

页码：3367 / 3372

页数：6

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