CAR T cell combination therapies to treat cancer

被引：40

作者：

Uslu, Ugur ^{[1
,2
]}

Castelli, Sofia ^{[1
,2
]}

June, Carl H. ^{[1
,2
,3
]}

机构：

[1] Univ Penn, Perelman Sch Med, Ctr Cellular Immunotherapies, Philadelphia, PA 19104 USA

[2] Univ Penn, Parker Inst Canc Immunotherapy, Philadelphia, PA 19104 USA

[3] Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA 19104 USA

来源：

CANCER CELL | 2024年 / 42卷 / 08期

关键词：

IBRUTINIB; LYMPHOMA;

D O I：

10.1016/j.ccell.2024.07.002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chimeric antigen receptor (CAR) T cells are effectively used in certain hematological malignancies, though tumor relapse and limited success in solid tumors persist. Recent efforts focus on developing combination treatments to enhance outcomes and safety. Here, we provide a comprehensive overview of such combinatorial approaches and a consideration of ongoing clinical trials.

引用

页码：1319 / 1325

页数：7

共 15 条

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