Fire Needling Therapy versus Usual Care for Parkinson's Disease-Related Chronic Pain: A Pilot Randomized Controlled Trial

被引：1

作者：

Wang, Mina ^{[1
,2
]}

Ren, Yashuo ^{[1
]}

Xiao, Hongli ^{[1
]}

Liu, Anming ^{[1
,2
]}

Ma, Chunying ^{[2
]}

Li, Zhuohao ^{[2
]}

Wang, Zixi ^{[2
]}

Xia, Qiuyu ^{[2
]}

Dou, Pu ^{[1
]}

Li, Bin ^{[2
]}

Chen, Peng ^{[2
]}

机构：

[1] Beijing Univ Chinese Med, Grad Sch, Beijing 100029, Peoples R China

[2] Capital Med Univ, Beijing Hosp Tradit Chinese Med, Dept Acupuncture & Moxibust, Beijing 100010, Peoples R China

来源：

JOURNAL OF PAIN RESEARCH | 2024年 / 17卷

关键词：

parkinson's disease; pain; fire needling therapy; acupuncture; pilot randomized controlled trial; RATING-SCALE; ACUPUNCTURE;

D O I：

10.2147/JPR.S485481

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: Parkinson's disease (PD)-related chronic pain is a prevalent non-motor symptom, this study aimed to detect the effect and safety of fire needling therapy (FNT) for PD-related chronic pain relief.<br /> Methods: Patients with PD-related chronic pain were randomly allocated to FNT group and control group with a treatment phase of 8 weeks and a follow-up phase of 4 weeks. Primary outcome was the King's Parkinson's Pain Scale (KPPS), Secondary outcomes included Visual Analogue Scale (VAS), Unified Parkinson's Disease Rating Scale-III (UPDRS-III), and the Parkinson's Disease Questionnaire-39 (PDQ-39). Study was registered on Chinese Clinical Trial Registry (Registered number: ChiCTR2400084951).<br /> Results: 60 participants were randomized, with 30 in the FNT group and 30 in the control group. KPPS was significantly influenced by the interaction of treatment and time, with a significant reduction in pain observed in the FNT group compared to the control group at Week 4 (difference [95% CI]: - 20.693[- 27.619,-13.767], P< 0.001), Week 8 (difference [95% CI]: 44.680[- 52.359,-37.000], P< 0.001), and Week 12 (difference [95% CI]: - 44.982[- 52.771,-37.193], P< 0.001). For VAS, UPDRS-III, and PDQ-39, there were significant differences between groups at Week 4, Week 8, and Week 12.<br /> Conclusion: FNT could be an effective and safe method for managing PD-related chronic pain. However, large-sample studies conducted in multiple centers are necessary to further verify the findings in the future.

引用

页码：3021 / 3030

页数：10