Urban greening is a major goal in policies for sustainable cities, and spatial planners are nowadays strongly interested in the benefits of greenspace for the well-being of urban residents. We present a novel, model-based approach to support the development of effective greening strategies. The approach is quantitative and spatially explicit and accounts for multiple health benefits as well as burdens. In our study, we applied this generic approach to the city of Maastricht (The Netherlands) and conducted an integrated, city-scale assessment of the health benefits and burdens of four urban greenspace designs. These included: 'No greenspace', 'Current greenspace', 'Green parking lots and squares', and 'Optimized greenspace locations'. For each greenspace design, indicator values were calculated for five determinants of health and well-being: heat stress, air pollution, perceived unsafety, unattractive views, and tick-bite risk. To assess the health contribution of urban greenspace in a given design, these indicator values were compared with the values in the 'No greenspace' design. The study produced clear, quantitative conclusions about the health benefits and burdens of the urban greenspace designs for the case of Maastricht but also generated novel, more general insights relevant to the planning of urban greenspace for health and well-being. These insights concern the importance of translating health policy objectives into specific target values or thresholds and the importance of 'smart' choices in greenspace type and location that can effectively reduce trade-offs between health benefits and burdens, as well as the insights that adding more greenery not always improves urban health and that urban greenspace alone cannot solve major air pollution problems. The priorities for future research, which will address the limitations of the presented approach, concern a further expansion of the range of health benefits and burdens covered by the model and the development of a common metric for the entire range of health benefits and burdens to optimize greenspace design and maximize its overall net health benefit.
