Decapping NAD-RNAs: TIR domain-containing proteins stand out for specificity

被引：0
|
作者：
Cao, Dechang [1 ]
机构：
[1] Chinese Acad Sci, Kunming Inst Bot, Germplasm Bank Wild Species, Kunming 650201, Yunnan, Peoples R China
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 2024年 / 49卷 / 06期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/j.tibs.2024.04.004
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A recently characterized RNA modification is NAD(+)-modified RNAs (NAD-RNAs). Various enzymes decap NAD-RNAs, and Wang and Yu et al. now describe another, namely Toll/interleukin-1 receptor (TIR) domain-containing proteins of bacteria and Archaea. TIR decapping products are a specific variant of cyclic ADP ribose (ADPR)-RNAs (v-cADPR-RNAs), opening a new window to the NAD-RNA world.
引用
收藏
页码：477 / 479
页数：3
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