Plant-derived exosomes: A Green Nanomedicine for Cancer

被引:2
作者
Sonar, Swarup [1 ]
Anand, Krishnan [2 ]
机构
[1] Saveetha Inst Med & Tech Sci, Saveetha Med Coll & Hosp, Ctr Global Hlth Res, Chennai, Tamil Nadu, India
[2] Univ Free State, Sch Pathol, Dept Chem Pathol, Bloemfontein, South Africa
来源
CLINICAL AND TRANSLATIONAL DISCOVERY | 2024年 / 4卷 / 04期
关键词
cancer therapeutic; clinical trials; drug delivery; plant exosomes; DRUG-DELIVERY; VESICLES; SIRNA;
D O I
10.1002/ctd2.333
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Exosomes are signalling molecules related to cell-to-cell communication. Based on sources (plants, stem cells, and immune cells derived exosomes) it offers promising therapeutic activity against cancer. Plant-derived exosomes (PDEs) are natural extracellular vesicles (EVs) that are potent to provide organic precision nanomedicine to cancer therapeutics including targeted drug delivery. PDEs are gaining attention due to their safety and efficacy. There are plenty of different sources of PDEs in nature. This article explores various plants such as carrots, ginger, lemons, cabbages, blueberries, oranges, tomatoes, grapefruits, and tea leaves, which provide exosomes with distinct therapeutic properties, including anti-inflammatory, antioxidant, and anticancer activities. PDEs exhibit significant potential in drug delivery. Ongoing research and clinical trials predict that PDEs will become effective, and affordable solutions for cancer treatment.
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页数:3
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