The prognostic role of markers of systemic inflammation in patients with metastatic lung cancer receiving immunotherapy: A comprehensive review of the literature

被引:0
作者
Zlatanova, Tanya [1 ]
Arabadjiev, Jeliazko [1 ]
机构
[1] Acibadem City Clin UMHAT Tokuda, Sofia, Bulgaria
关键词
markers of systemic inflammation; lung cancer; immunotherapy; LYMPHOCYTE RATIO PREDICTS; NEUTROPHIL; INDEX; SURVIVAL; PLATELET;
D O I
10.3897/pharmacia.71.e115558
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Lung carcinoma stands as a prevalent malignancy characterized by a distressingly elevated fatality rate. Immunotherapy, administered either as a monotherapy or together with chemotherapy, represents the primary therapeutic approach for the majority of individuals grappling with advanced non-small cell lung cancer. The influence of systemic inflammation in fostering cancer dissemination and progression is a well-documented phenomenon. This literature review examines contemporary indices and scoring systems, which have emerged as informative indicators of systemic inflammation in recent years. These indices and scores are valuable prognostic and predictive elements in assessing treatment response among patients with metastatic lung cancer undergoing immunotherapeutic treatment.
引用
收藏
页码:1 / 7
页数:7
相关论文
共 50 条
[41]   Prognostic factors for response and survival in patients with metastatic melanoma receiving immunotherapy [J].
Keilholz, U ;
Scheibenbogen, C ;
Sommer, M ;
Pritsch, M ;
Geuke, AM .
MELANOMA RESEARCH, 1996, 6 (02) :173-178
[42]   Prognostic significance of the systemic immune inflammation index in patients with metastatic and unresectable pancreatic cancer [J].
Han, Rongshuang ;
Tian, Zibin ;
Jiang, Yueping ;
Guan, Ge ;
Wang, Xiaowei ;
Sun, Xueguo ;
Yu, Yanan ;
Jing, Xue .
FRONTIERS IN SURGERY, 2022, 9
[43]   Joint prognostic effect of obesity and chronic systemic inflammation in patients with metastatic colorectal cancer [J].
Shah, Manasi S. ;
Fogelman, David R. ;
Raghav, Kanwal Pratap Singh ;
Heymach, John V. ;
Tran, Hai T. ;
Jiang, Zhi-Qin ;
Kopetz, Scott ;
Daniel, Carrie R. .
CANCER, 2015, 121 (17) :2968-2975
[44]   Prognostic model integrating histology, systemic inflammation, and recurrence status predicts immunotherapy response in advanced non-small-cell lung cancer patients [J].
Moiseenko, F. V. ;
Krasavina, M. A. ;
Agranov, I. R. ;
Artemieva, E. V. ;
Oganesian, A. P. ;
Gabina, A. S. ;
Makarkina, M. L. ;
Elsakova, E. O. ;
Henshtein, V. A. ;
Volkov, N. M. ;
Egorenkov, V. V. ;
Moiseenko, V. M. ;
Fedyanin, M. Yu. ;
Kopeina, G. S. ;
Zhivotovsky, B. ;
Zamaraev, A. V. .
BIOLOGY DIRECT, 2025, 20 (01)
[45]   The prognostic role of systemic immune-inflammation index, SII, in Metastatic Castration-Resistant Prostate Cancer patients [J].
Uzun, Mehmet ;
Gokcek, Savas ;
Kaya, Erhan ;
Semiz, Huseyin Salih .
DISCOVER ONCOLOGY, 2025, 16 (01)
[46]   Prognostic value of systemic inflammation score in patients with esophageal cancer [J].
Yoneda, Akira ;
Ogata, Ryosuke ;
Ryu, Shintaro ;
Yoshino, Kyohei ;
Fukui, Saeko ;
Kugiyama, Tota ;
Kitasato, Amane ;
Sugiyama, Nozomu ;
Takeshita, Hiroaki ;
Minami, Shigeki ;
Kuroki, Tamotsu .
ANNALS OF MEDICINE AND SURGERY, 2024, 86 (07) :3852-3855
[47]   Thromboembolic risk in patients with lung cancer receiving systemic therapy [J].
Madison, Cecelia J. ;
Melson, Ryan A. ;
Conlin, Michael J. ;
Gundle, Kenneth R. ;
Thompson, Reid F. ;
Calverley, David C. .
BRITISH JOURNAL OF HAEMATOLOGY, 2021, 194 (01) :179-190
[48]   The Role of Immunotherapy or Immuno-Chemotherapy in Non-Small Cell Lung Cancer: A Comprehensive Review [J].
Mohamed, Shehab ;
Bertolaccini, Luca ;
Galetta, Domenico ;
Petrella, Francesco ;
Casiraghi, Monica ;
de Marinis, Filippo ;
Spaggiari, Lorenzo .
CANCERS, 2023, 15 (09)
[49]   Prognostic impact of blood transfusion in patients with metastatic non-small cell lung cancer receiving chemotherapy [J].
Sakin, Abdullah ;
Sahin, Suleyman ;
Yasar, Nurgul ;
Demir, Cumhur ;
Arici, Serdar ;
Geredeli, Caglayan ;
Cihan, Sener .
LUNG CANCER, 2019, 133 :38-44
[50]   Prognostic value of pretreatment systemic inflammatory markers in patients with stage I endometrial cancer [J].
Ahn, Jung Hwan ;
Lee, Sung Jong ;
Yoon, Joo Hee ;
Park, Dong Choon ;
Kim, Sang Il .
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2022, 19 (14) :1989-1994