Predictors of Diabetic Retinopathy in Type 2 Diabetes: A Cross-Sectional Study

被引:4
作者
Ivanescu, Adriana [1 ,2 ]
Popescu, Simona [1 ,3 ]
Ivanescu, Radu [2 ]
Potra, Monica [1 ]
Timar, Romulus [1 ,3 ]
机构
[1] Victor Babes Univ Med & Pharm, Dept Internal Med 2, Timisoara 300041, Romania
[2] Opticlass Ophtalmol Clin, Timisoara 300012, Romania
[3] Pius Brinzeu Emergency Hosp, Dept Diabet, Timisoara 300723, Romania
关键词
type 2 diabetes mellitus; diabetic retinopathy; risk factors; quality of life; PREVALENCE; CATARACT;
D O I
10.3390/biomedicines12081889
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Background: Type 2 diabetes mellitus (T2DM) represents one of the most impacting health issues of the modern era, as it is associated with an extensive range of comorbidities. Diabetic retinopathy (DR) is one the utmost severe diabetes complications as it is one of the major causes of vision loss among these patients. Our present research aims to evaluate the most frequent risk factors related to the occurrence of DR in T2DM patients. Method: This study consisted of a research group of 302 participants, priorly diagnosed with T2DM, that were evaluated for the most important risk factors related to the occurrence of DR. Results: Patients had a median age of 64 years, 48% of them being women, with a 12-year median duration of DM and presenting a deficient glycaemic control echoed by a median HbA1C value of 7.5%. From the total number of participants, the total prevalence of DR in different stages of severity was 34.8% with a 95% CI. Statistically significant values were found regarding DM duration (p = 0.007), HbA1c > 7.2% (p = 0.001) and patients aged over 67 years (p = 0.0035), all these parameters being directly linked to DR. Conclusions: Older patients with T2DM that have a longer disease duration and simultaneous comorbidities present a higher risk of DR development, consequently a stringent management of these pathologies is needed.
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页数:14
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