Ex-situ machine perfusion in clinical liver transplantation: Current practices and future directions

被引：1
作者：
Nguyen, Michelle C. [1 ]
Li, Xingjie [1 ]
Linares, Natalia [2 ]
Jadlowiec, Caroline [1 ]
Moss, Adyr [1 ]
Reddy, Kunam S. [1 ]
Mathur, Amit K. [1 ]
机构：
[1] Mayo Clin Arizona, Dept Surg, Div Transplant Surg, Phoenix, AZ USA
[2] Mayo Clin, Alix Sch Med, Rochester, MN USA
来源：
LIVER TRANSPLANTATION | 2024年
关键词：
PRESERVATION; CRITERIA; DONATION; OUTCOMES; COST;
D O I：
10.1097/LVT.0000000000000428
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Ex-situ machine perfusion of the liver has surmounted traditional limitations associated with static cold storage in the context of organ preservation. This innovative technology has changed the landscape of liver transplantation by mitigating ischemia perfusion injury, offering a platform for continuous assessment of organ quality, and providing an avenue for optimizing use of traditionally marginal allografts. This review summarizes the contemporary clinical applications of machine perfusion devices, and discusses potential future strategies for real-time viability assessment, therapeutic interventions, and modulation of organ function after recovery.
引用
收藏
页码：531 / 544
页数：32
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