Leucocytosis during all-trans retinoic acid and arsenic trioxide treatment in acute promyelocytic leukaemia
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Yanada, Masamitsu
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Nagoya City Univ, East Med Ctr, 1-2-23 Wakamizu,Chikusa Ku, Nagoya 4648547, JapanNagoya City Univ, East Med Ctr, 1-2-23 Wakamizu,Chikusa Ku, Nagoya 4648547, Japan
Yanada, Masamitsu
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[1] Nagoya City Univ, East Med Ctr, 1-2-23 Wakamizu,Chikusa Ku, Nagoya 4648547, Japan
In patients with acute promyelocytic leukaemia (APL), differentiation syndrome (DS) is a life-threatening complication caused by the differentiating effect of all-trans retinoic acid (ATRA) and/or arsenic trioxide (ATO). Leucocytosis is frequently observed during induction therapy for APL and is intimately associated with the development of DS and its severity. The management of DS is particularly important due to the high likelihood of excellent outcomes for APL patients who successfully complete induction therapy. Commentary on: Cicconi et al. Leukocytosis during induction therapy with all-trans-retinoic acid and arsenic trioxide in acute promyelocytic leukemia predicts for differentiation syndrome and treatment-related complications. Br J Haematol 2024 (Online ahead of print). doi: .
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Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R ChinaUniv Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
Au, WY
Chim, CS
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Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R ChinaUniv Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
Chim, CS
Lie, AKW
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Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R ChinaUniv Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
Lie, AKW
Liang, R
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Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R ChinaUniv Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
Liang, R
Kwong, YL
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Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R ChinaUniv Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
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Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, ItalyUniv Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy
Breccia, Massimo
Molica, Matteo
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Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, ItalyUniv Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy
Molica, Matteo
Efficace, Fabio
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Univ Roma Tor Vergata, Ctr Data, Rome, Italy
Univ Roma Tor Vergata, Hlth Outcomes Res Unit, Italian Grp Adult Hematol Dis GIMEMA, Rome, ItalyUniv Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy
Efficace, Fabio
Minotti, Clara
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Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, ItalyUniv Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy
Minotti, Clara
Latagliata, Roberto
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Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, ItalyUniv Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy
Latagliata, Roberto
Foa, Robin
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Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, ItalyUniv Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy
Foa, Robin
Lo Coco, Francesco
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Univ Roma Tor Vergata, Dept Biopathol, Rome, Italy
Santa Lucia Fdn, Lab Neurooncohematol, Rome, ItalyUniv Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy