SIC position paper: Treat to prevent - intensive LDL cholesterol reduction in the patients at very high cardiovascular risk without a previous event. From ESC guidelines to clinical practice

被引：0

作者：

Filardi, Pasquale Perrone ^{[1
]}

Nardi, Ermanno ^{[1
]}

Agostoni, Piergiuseppe ^{[2
,3
]}

Barilla, Francesco ^{[4
]}

Calabro, Paolo ^{[5
]}

Ciccone, Marco Matteo ^{[6
]}

Curcio, Antonio ^{[7
]}

Indolfi, Ciro ^{[7
]}

Muscoli, Saverio ^{[8
]}

Nodari, Savina ^{[9
]}

Paolillo, Stefania ^{[1
]}

Patti, Giuseppe ^{[10
]}

Porto, Italo ^{[11
]}

Sinagra, Gianfranco ^{[12
]}

Gallo, Luca ^{[1
]}

Fontanarosa, Sara ^{[1
]}

Vizza, Carmine Dario ^{[13
]}

Gargiulo, Paola ^{[1
]}

机构：

[1] Univ Napoli Federico II, Dipartimento Sci Biomed Avanzate, Via S Pansini 5, I-80131 Naples, Italy

[2] IRCCS, Ctr Cardiol Monzino, Milan, Italy

[3] Univ Milan, Dipartimento Sci Clin Comunitk, Milan, Italy

[4] Univ Tor Vergata, Dipartimento Med Sistemi, Rome, Italy

[5] UOC Cardiol Clin, Padua, Italy

[6] Policlin Univ, UO Cardiol, Bari, Italy

[7] Magna Graecia Univ Catanzaro, Ist Cardiol, Dipartimento Sci Med & Chirurg, Catanzaro, Italy

[8] Fdn Policlin Tor Vergata, UOC Cardiol, Rome, Italy

[9] Univ Spedali Civili, UOC Cardiol Day Hosp, Brescia, Italy

[10] Azienda Osped Univ Maggiore Caritk, UO Cardiol, Novara, Italy

[11] IRCCS Osped Policlin San Martino, Malattie Cardiovasc, Genoa, Italy

[12] Univ Trieste, Azienda Sanitaria Univ Giuliano Isontina ASUGI, Dipartimento Cardiotoracovasc, Trieste, Italy

[13] Sapienza Univ Roma, Policlin Umberto 1, Dipartimento Sci Cardiovasc Resp, Roma, TX USA

来源：

GIORNALE ITALIANO DI CARDIOLOGIA | 2024年 / 25卷 / 07期

关键词：

Cardiovascular prevention; Cardiovascular risk score; Chronic kidney disease; Diabetes melli- tus; Familial hypercholesterolemia; LDL-cholesterol; Subclinical atherosclerosis; PERIPHERAL ARTERY-DISEASE; INTIMA-MEDIA THICKNESS; CHRONIC KIDNEY-DISEASE; FAMILIAL HYPERCHOLESTEROLEMIA; MYOCARDIAL-INFARCTION; POLYVASCULAR DISEASE; EUROPEAN-SOCIETY; SUBCLINICAL ATHEROSCLEROSIS; COLLABORATIVE METAANALYSIS; CAROTID ATHEROSCLEROSIS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiovascular (CV) diseases account for over 4 million deaths every year in Europe and over 220 000 deaths in Italy, representing the leading cause of morbidity and mortality worldwide. The European Society of Cardiology (ESC) guidelines have visionary included in the at very high CV risk group patients without previous acute ischemic events, such as those with subclinical atherosclerosis, chronic coronary syndrome or peripheral arterial disease, familial hypercholesterolemia, diabetes mellitus with target organ damage or multiple associated risk factors, and those with high calculated CV risk score, recommending to consider them and to achieve the same LDL-cholesterol targets as for secondary prevention patients. The aim of this position paper is to provide an updated overview of ESC guidelines that focuses on these patient categories to raise awareness within the clinical community regarding CV risk reduction in this specific epidemiological context.

引用

页码：530 / 540

页数：11