Objective: To investigate the prevalence of lower urinary tract symptoms (LUTS) in a Finnish cohort of patients who had undergone feminizing genitoplasty in childhood. Patients and methods: Information on LUTS was assessed using the Danish Prostatic Symptom Score questionnaire: 24 out of 45 females (53%) returned the questionnaire; 16 patients with prenatal androgen exposure (congenital adrenal hyperplasia = CAH group) and eight with androgen insensitivity (AIS group). Results: Urge urinary incontinence was reported by 13% of the patients in both the CAH and AIS groups and by 15% of the controls. Stress urinary incontinence was reported by 31% of the patients in the CAH group, 13% of the patients in the AIS group and 22% of the controls. Distressing voiding symptoms were reported by 19% of the patients in the CAH group, 13% of the patients in the AIS group and 28% of the controls, and of these straining and incomplete emptying were the most prevalent. Conclusions: LUTS are as common in female DSD patients with feminizing genitoplasty as they are in controls. Some degree of distressing incontinence occurred in 13%-25% of the young female patients and the controls. (C) 2011 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.
机构:
Hadassah Hebrew Univ Med Ctr, Dept Obstet & Gynecol, Jerusalem, IsraelHadassah Hebrew Univ Med Ctr, Dept Obstet & Gynecol, Jerusalem, Israel
Shveiky, David
Iglesia, Cheryl B.
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MedStar Washington Hosp Ctr, Sect Female Pelv Med & Reconstruct Surg, Washington, DC USA
Georgetown Univ, Washington Hosp Ctr, Dept Obstet & Gynecol & Urol, Washington, DC USAHadassah Hebrew Univ Med Ctr, Dept Obstet & Gynecol, Jerusalem, Israel
Iglesia, Cheryl B.
Antosh, Danielle D.
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MedStar Washington Hosp Ctr, Sect Female Pelv Med & Reconstruct Surg, Washington, DC USA
Georgetown Univ, Washington Hosp Ctr, Dept Obstet & Gynecol & Urol, Washington, DC USAHadassah Hebrew Univ Med Ctr, Dept Obstet & Gynecol, Jerusalem, Israel
Antosh, Danielle D.
Kudish, Bela I.
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MedStar Washington Hosp Ctr, Sect Female Pelv Med & Reconstruct Surg, Washington, DC USA
Georgetown Univ, Washington Hosp Ctr, Dept Obstet & Gynecol & Urol, Washington, DC USAHadassah Hebrew Univ Med Ctr, Dept Obstet & Gynecol, Jerusalem, Israel
Kudish, Bela I.
Peterson, Joanna
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MedStar Washington Hosp Ctr, Sect Female Pelv Med & Reconstruct Surg, Washington, DC USA
Georgetown Univ, Washington Hosp Ctr, Dept Obstet & Gynecol & Urol, Washington, DC USAHadassah Hebrew Univ Med Ctr, Dept Obstet & Gynecol, Jerusalem, Israel
Peterson, Joanna
Huang, Chun-Chin
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Medstar Res Inst, Dept Biostat & Epidemiol, Washington, DC USAHadassah Hebrew Univ Med Ctr, Dept Obstet & Gynecol, Jerusalem, Israel
Huang, Chun-Chin
Spies, James B.
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Georgetown Univ, Sch Med, Dept Radiol, Washington, DC USAHadassah Hebrew Univ Med Ctr, Dept Obstet & Gynecol, Jerusalem, Israel
机构:
VA Ctr Excellence Stress & Mental Hlth, San Diego, CA USA
Univ Calif San Diego, San Diego, CA 92103 USAVA Ctr Excellence Stress & Mental Hlth, San Diego, CA USA
Afari, Niloofar
Gasperi, Marianna
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VA Ctr Excellence Stress & Mental Hlth, San Diego, CA USA
Univ Calif San Diego, San Diego, CA 92103 USAVA Ctr Excellence Stress & Mental Hlth, San Diego, CA USA
Gasperi, Marianna
Forsberg, Christopher W.
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VA Puget Sound Hlth Care Syst, Seattle Epidemiol Res & Informat Ctr, Vietnam Era Twin Registry, Seattle, WA USAVA Ctr Excellence Stress & Mental Hlth, San Diego, CA USA
Forsberg, Christopher W.
Goldberg, Jack
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VA Puget Sound Hlth Care Syst, Seattle Epidemiol Res & Informat Ctr, Vietnam Era Twin Registry, Seattle, WA USA
Univ Washington, Seattle, WA 98195 USAVA Ctr Excellence Stress & Mental Hlth, San Diego, CA USA
Goldberg, Jack
Buchwald, Dedra
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Washington State Univ, Elson S Floyd Coll Med, Seattle, WA USA
Washington State Univ, Elson S Floyd Coll Med, Spokane, WA USAVA Ctr Excellence Stress & Mental Hlth, San Diego, CA USA
Buchwald, Dedra
Krieger, John N.
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Univ Washington, Seattle, WA 98195 USAVA Ctr Excellence Stress & Mental Hlth, San Diego, CA USA
机构:
Eastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USAEastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USA
Takacs, Peter
Larson, Kindra
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Eastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USAEastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USA
Larson, Kindra
Scott, Lauren
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Eastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USAEastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USA
Scott, Lauren
Cunningham, Tina D.
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Eastern Virginia Med Sch, Ctr Hlth Analyt & Discovery, Norfolk, VA 23507 USAEastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USA
Cunningham, Tina D.
DeShields, Sarah C.
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机构:
Eastern Virginia Med Sch, Ctr Hlth Analyt & Discovery, Norfolk, VA 23507 USAEastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USA
DeShields, Sarah C.
Abuhamad, Alfred
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Eastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USAEastern Virginia Med Sch, Div Female Pelv Med & Reconstruct Surg, Dept Obstet & Gynecol, 825 Fairfax Ave,Suite 526, Norfolk, VA 23507 USA
机构:
Univ Roma La Sapienza, StAndrea Hosp, Dept Urol, Via Grottarossa 1035, I-00189 Rome, ItalyUniv Roma La Sapienza, StAndrea Hosp, Dept Urol, Via Grottarossa 1035, I-00189 Rome, Italy
De Nunzio, Cosimo
Lombardo, Riccardo
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Univ Roma La Sapienza, StAndrea Hosp, Dept Urol, Via Grottarossa 1035, I-00189 Rome, ItalyUniv Roma La Sapienza, StAndrea Hosp, Dept Urol, Via Grottarossa 1035, I-00189 Rome, Italy
Lombardo, Riccardo
Tema, Giorgia
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Univ Roma La Sapienza, StAndrea Hosp, Dept Urol, Via Grottarossa 1035, I-00189 Rome, ItalyUniv Roma La Sapienza, StAndrea Hosp, Dept Urol, Via Grottarossa 1035, I-00189 Rome, Italy
Tema, Giorgia
Tubaro, Andrea
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Univ Roma La Sapienza, StAndrea Hosp, Dept Urol, Via Grottarossa 1035, I-00189 Rome, ItalyUniv Roma La Sapienza, StAndrea Hosp, Dept Urol, Via Grottarossa 1035, I-00189 Rome, Italy