Adalimumab as treatment for neurosarcoidosis: A case series

被引：1

作者：

Shen, Jeffrey ^{[1
]}

Sugita, Megumi ^{[2
]}

Linares-Lopez, Andrea ^{[2
]}

Shah, Suma ^{[3
]}

Eckstein, Christopher ^{[3
]}

Lackey, Elijah ^{[3
,4
]}

机构：

[1] Duke Univ Hosp, Dept Rheumatol, Durham, NC USA

[2] Duke Univ Hosp, Dept Neurol, Durham, NC USA

[3] Duke Univ Hosp, Dept MS & Neuroimmunol, Durham, NC USA

[4] Duke Univ Hosp, 2301 Erwin Rd, Durham, NC 27705 USA

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 2024年 / 460卷

关键词：

Neurosarcoidosis; Neuroimmunology; Adalimumab; TNF-alpha inhibitors; SARCOIDOSIS; INFLIXIMAB;

D O I：

10.1016/j.jns.2024.123018

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Sarcoidosis is a disease characterized by non-caseating granulomas that can involve the central nervous system as neurosarcoidosis. This challenging disease is currently managed with high dose steroids, and sometimes the addition of infliximab. Other TNA-alpha inhibitors have not been studied as rigorously. We discovered ten neurosarcoidosis patients who were on an alternative TNA-alpha inhibitor, adalimumab. Eight patients had a positive response clinically and radiographically to adalimumab.

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页数：5

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