Adalimumab as treatment for neurosarcoidosis: A case series

被引：1
作者：
Shen, Jeffrey [1 ]
Sugita, Megumi [2 ]
Linares-Lopez, Andrea [2 ]
Shah, Suma [3 ]
Eckstein, Christopher [3 ]
Lackey, Elijah [3 ,4 ]
机构：
[1] Duke Univ Hosp, Dept Rheumatol, Durham, NC USA
[2] Duke Univ Hosp, Dept Neurol, Durham, NC USA
[3] Duke Univ Hosp, Dept MS & Neuroimmunol, Durham, NC USA
[4] Duke Univ Hosp, 2301 Erwin Rd, Durham, NC 27705 USA
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 2024年 / 460卷
关键词：
Neurosarcoidosis; Neuroimmunology; Adalimumab; TNF-alpha inhibitors; SARCOIDOSIS; INFLIXIMAB;
D O I：
10.1016/j.jns.2024.123018
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Sarcoidosis is a disease characterized by non-caseating granulomas that can involve the central nervous system as neurosarcoidosis. This challenging disease is currently managed with high dose steroids, and sometimes the addition of infliximab. Other TNA-alpha inhibitors have not been studied as rigorously. We discovered ten neurosarcoidosis patients who were on an alternative TNA-alpha inhibitor, adalimumab. Eight patients had a positive response clinically and radiographically to adalimumab.
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页数：5
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