Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM

被引：89

作者：

Chang, Christina C. ^{[1
,2
,3
]}

Harrison, Thomas S. ^{[4
,5
,6
]}

Bicanic, Tihana A. ^{[4
,5
,6
]}

Chayakulkeeree, Methee ^{[7
]}

Sorrell, Tania C. ^{[8
,9
]}

Warris, Adilia ^{[6
,11
]}

Hagen, Ferry ^{[12
,13
,14
]}

Spec, Andrej ^{[15
]}

Oladele, Rita ^{[16
]}

Govender, Nelesh P. ^{[4
,6
,17
,18
]}

Chen, Sharon C. ^{[8
,9
,19
]}

Mody, Christopher H. ^{[20
]}

Groll, Andreas H. ^{[21
,22
,23
]}

Chen, Yee-Chun ^{[24
,25
,26
]}

Lionakis, Michail S. ^{[27
]}

Alanio, Alexandre ^{[28
]}

Castaneda, Elizabeth ^{[29
]}

Lizarazo, Jairo ^{[30
]}

Vidal, Jose E. ^{[31
,32
,33
]}

Takazono, Takahiro ^{[34
,35
]}

Hoenigl, Martin ^{[36
,37
]}

Alffenaar, Jan-Willem ^{[8
,10
,38
]}

Gangneux, Jean-Pierre ^{[39
,40
]}

Soman, Rajeev ^{[41
,42
,43
]}

Zhu, Li-Ping ^{[44
]}

Bonifaz, Alexandro ^{[45
]}

Jarvis, Joseph N. ^{[46
,47
]}

Day, Jeremy N. ^{[48
]}

Klimko, Nikolai ^{[49
]}

Salmanton-Garcia, Jon ^{[50
,51
,52
,53
,54
]}

Jouvion, Gregory ^{[55
,56
,57
]}

Meya, David B. ^{[58
]}

Lawrence, David ^{[46
,47
]}

Rahn, Sebastian ^{[50
,51
,52
,53
,54
]}

Bongomin, Felix ^{[59
]}

McMullan, Brendan J. ^{[60
,61
]}

Sprute, Rosanne ^{[50
,51
,52
,53
,54
]}

Nyazika, Tinashe K. ^{[62
]}

Beardsley, Justin ^{[8
,9
]}

Carlesse, Fabianne ^{[63
,64
]}

Heath, Christopher H. ^{[65
,66
,67
]}

Ayanlowo, Olusola O. ^{[68
]}

Mashedi, Olga M. ^{[69
]}

Queiroz-Telles Filho, Flavio ^{[70
]}

Hosseinipour, Mina C. ^{[71
,72
]}

Patel, Atul K. ^{[73
]}

Temfack, Elvis ^{[74
]}

Singh, Nina ^{[75
]}

Cornely, Oliver A. ^{[50
,51
,52
,53
,54
,76
]}

Boulware, David R. ^{[77
]}

机构：

[1] Alfred Hosp, Dept Infect Dis, Melbourne, Vic 3181, Australia

[2] Monash Univ, Cent Clin Sch, Dept Infect Dis, Melbourne, Vic, Australia

[3] Ctr AIDS Programme Res South Africa, Durban, South Africa

[4] St Georges Univ London, Inst Infect & Immun, London, England

[5] St Georges Univ Hosp NHS Fdn Trust, Clin Acad Grp Infect & Immun, London, England

[6] Univ Exeter, Med Res Ctr Med Mycol, Exeter, England

[7] Mahidol Univ, Siriraj Hosp, Dept Med, Div Infect Dis & Trop Med,Fac Med, Bangkok, Thailand

[8] Univ Sydney, Sydney Infect Dis Inst, Sydney, NSW, Australia

[9] Westmead Hosp, Dept Infect Dis, Westmead, NSW, Australia

[10] Westmead Hosp, Dept Pharm, Westmead, NSW, Australia

[11] Great Ormond St Hosp Sick Children, Dept Infect Dis, London, England

[12] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, Fac Sci, Amsterdam, Netherlands

[13] Westerdijk Fungal Biodivers Inst, Dept Med Mycol, Utrecht, Netherlands

[14] Univ Med Ctr Utrecht, Dept Med Microbiol, Utrecht, Netherlands

[15] Washington Univ, Sch Med, Dept Med, Div Infect Dis, St Louis, MO USA

[16] Univ Lagos, Coll Med, Lagos, Nigeria

[17] Univ Witwatersrand, Fac Hlth Sci, Sch Pathol, Dept Clin Microbiol & Infect Dis, Johannesburg, South Africa

[18] Univ Cape Town, Fac Hlth Sci, Div Med Microbiol, Cape Town, South Africa

[19] Inst Clin Pathol & Med Res, New South Wales Hlth Pathol, Ctr Infect Dis & Microbiol Lab Serv, Westmead, NSW, Australia

[20] Univ Calgary, Snyder Inst Chron Dis, Dept Microbiol Immunol & Infect Dis, Dept Med, Calgary, AB, Canada

[21] Univ Childrens Hosp, Infect Dis Res Program, Munster, Germany

[22] Univ Childrens Hosp, Ctr Bone Marrow Transplantat, Munster, Germany

[23] Univ Childrens Hosp, Dept Pediat Hematol Oncol, Munster, Germany

[24] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan

[25] Coll Med, Taipei, Taiwan

[26] Natl Hlth Res Inst, Natl Inst Infect Dis & Vaccinol, Zhunan, Taiwan

[27] NIH, Fungal Pathogenesis Sect, Lab Clin Immunol & Microbiol, Natl Inst Allergy & Infect Dis, Bethesda, MD USA

[28] Univ Paris Cite, Dept Mycol, Grp Rech Mycol Translat, Inst Pasteur,Ctr Natl Reference Mycoses Invas & An, Paris, France

[29] Inst Nacl Salud, Bogota, Colombia

[30] Univ Pamplona, Hosp Univ Erasmo Meoz, Fac Hlth, Dept Internal Med, Cucuta, Colombia

[31] Inst Infectol Emilio Ribas, Dept Neurol, Sao Paulo, Brazil

[32] Univ Sao Paulo, Hosp Clin, Dept Molestias Infecciosas & Parasitarias, Fac Med, Sao Paulo, Brazil

[33] Univ Sao Paulo, Fac Med, Inst Med Trop, Sao Paulo, Brazil

[34] Nagasaki Univ, Grad Sch Biomed Sci, Dept Infect Dis, Nagasaki, Japan

[35] Nagasaki Univ Hosp, Dept Resp Med, Nagasaki, Japan

[36] Med Univ Graz, European Confederat Med Mycol Excellence Ctr Med M, Div Infect Dis, Translat Med Mycol Res Unit, Graz, Austria

[37] BioTechMed, Graz, Austria

[38] Univ Sydney, Fac Med & Hlth, Sch Pharm, Sydney, NSW, Australia

[39] Univ Rennes, Inst Hlth Environm & Work Res Irset, Inserm UMR S 1085, Rennes, France

[40] Univ Hosp Rennes, Ctr Natl Reference Mycoses Invas & Antifong LA Asp, Lab Parasitol & Mycol, Rennes, France

[41] Jupiter Hosp, Pune, India

[42] Deenanath Mangeshkar Hosp, Pune, India

[43] Hinduja Hosp, Mumbai, India

[44] Fudan Univ, Huashan Hosp, Natl Med Ctr Infect Dis, Dept Infect Dis,Shanghai Key Lab Infect Dis & Bios, Shanghai, Peoples R China

[45] Univ Nacl Autonoma Mexico, Hosp Gen Mexico, Dermatol Serv, Mycol Sect, Mexico City, Mexico

[46] London Sch Hyg & Trop Med, Fac Infect & Trop Dis, Dept Clin Res, London, England

[47] Botswana Harvard AIDS Inst Partnership, Gaborone, Botswana

[48] Royal Devon & Exeter Univ Hosp NHS Trust, Dept Clin Microbiol & Infect, Exeter, England

[49] I Mechnikov North Western State Med Univ, Dept Clin Mycol Allergy & Immunol, St Petersburg, Russia

[50] Univ Cologne, Fac Med, Translat Res, Cologne Excellence Cluster Cellular Stress Respons, Cologne, Germany

来源：

LANCET INFECTIOUS DISEASES | 2024年 / 24卷 / 08期

基金：

美国国家卫生研究院; 英国科研创新办公室;

关键词：

RECONSTITUTION INFLAMMATORY SYNDROME; HIGH-DOSE FLUCONAZOLE; HIV-INFECTED PATIENTS; ORGAN TRANSPLANT RECIPIENTS; LIPOSOMAL AMPHOTERICIN-B; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; ELEVATED INTRACRANIAL-PRESSURE; ACTIVE ANTIRETROVIRAL THERAPY; CLINICAL-PRACTICE GUIDELINES; PLACEBO-CONTROLLED TRIAL;

D O I：

10.1016/S1473-3099(23)00731-4

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Cryptococcosis is a major worldwide disseminated invasive fungal infection. Cryptococcosis, particularly in its most lethal manifestation of cryptococcal meningitis, accounts for substantial mortality and morbidity. The breadth of the clinical cryptococcosis syndromes, the different patient types at-risk and affected, and the vastly disparate resource settings where clinicians practice pose a complex array of challenges. Expert contributors from diverse regions of the world have collated data, reviewed the evidence, and provided insightful guideline recommendations for health practitioners across the globe. This guideline offers updated practical guidance and implementable recommendations on the clinical approaches, screening, diagnosis, management, and follow-up care of a patient with cryptococcosis and serves as a comprehensive synthesis of current evidence on cryptococcosis. This Review seeks to facilitate optimal clinical decision making on cryptococcosis and addresses the myriad of clinical complications by incorporating data from historical and contemporary clinical trials. This guideline is grounded on a set of core management principles, while acknowledging the practical challenges of antifungal access and resource limitations faced by many clinicians and patients. More than 70 societies internationally have endorsed the content, structure, evidence, recommendation, and pragmatic wisdom of this global cryptococcosis guideline to inform clinicians about the past, present, and future of care for a patient with cryptococcosis.

引用

页码：e495 / e512

页数：18

共 175 条

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