Tailoring Treatment in Cardiovascular Diseases: The Role of Targeted Therapies

被引：2
作者：
Dankar, Razan [1 ,2 ]
Wehbi, Jad [1 ,2 ]
Refaat, Marwan M. [1 ,2 ]
机构：
[1] Amer Univ Beirut, Fac Med & Med Ctr, Dept Biochem & Mol Genet, POB 11-0236, Beirut, Lebanon
[2] Amer Univ Beirut, Fac Med & Med Ctr, Dept Internal Med, Div Endocrinol, POB 11-0236, Beirut, Lebanon
来源：
PHARMACEUTICS | 2024年 / 16卷 / 04期
关键词：
targeted therapy; cardiovascular disease; monoclonal antibodies (mAbs); bispecific antibodies (BsAbs); nucleic acid drugs; cell therapy; nanoparticles; precision medicine; REGULATORY T-CELLS; ACUTE MYOCARDIAL-INFARCTION; HEART-FAILURE; DOUBLE-BLIND; STEM-CELLS; IN-VIVO; RISK; INHIBITION; ABCIXIMAB; DELIVERY;
D O I：
10.3390/pharmaceutics16040461
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality around the globe. To address this public health burden, innovative therapeutic agents are being developed to specifically target molecular and genetic markers. Various therapeutic modalities have been implemented, including vaccines, monoclonal or bispecific antibodies, and gene-based therapies. Such drugs precisely target the underlying disease pathophysiology, aiming at notable molecules such as lipid metabolism regulators, proinflammatory cytokines, and growth factors. This review focuses on the latest advancements in different targeted therapies. It provides an insightful overview of the current landscape of targeted cardiovascular therapies, highlighting promising strategies with potential to transform the treatment of CVDs into an era of precision medicine.
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页数：19
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